胰岛素抵抗组织中的胰岛素受体激酶缺陷及其在非胰岛素依赖型糖尿病发病机制中的作用。 - Suppr

Suppr

超能文献

Insulin receptor kinase defects in insulin-resistant tissues and their role in the pathogenesis of NIDDM.

作者信息

Häring H, Obermaier-Kusser B

机构信息

Institut für Diabetesforschung, München, Federal Republic of Germany.

出版信息

Diabetes Metab Rev. 1989 Aug;5(5):431-41. doi: 10.1002/dmr.5610050502.

DOI:10.1002/dmr.5610050502

PMID:2547553

Abstract

摘要

相似文献

Insulin receptor kinase defects in insulin-resistant tissues and their role in the pathogenesis of NIDDM.胰岛素抵抗组织中的胰岛素受体激酶缺陷及其在非胰岛素依赖型糖尿病发病机制中的作用。

Diabetes Metab Rev. 1989 Aug;5(5):431-41. doi: 10.1002/dmr.5610050502.

Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.非胰岛素依赖型糖尿病患者脂肪细胞中胰岛素受体的激酶活性降低。

J Clin Invest. 1987 Jan;79(1):240-50. doi: 10.1172/JCI112789.

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.肥胖-糖尿病中胰岛素受体酪氨酸激酶活性降低。肿瘤坏死因子-α的核心作用。

J Clin Invest. 1994 Oct;94(4):1543-9. doi: 10.1172/JCI117495.

Insulin receptor kinase defects as a possible cause of cellular insulin resistance.胰岛素受体激酶缺陷可能是细胞胰岛素抵抗的一个原因。

Diabete Metab. 1987 Jul;13(3 Pt 2):284-93.

Insulin-receptor kinase activity of adipose tissue from morbidly obese humans with and without NIDDM.患有和未患有非胰岛素依赖型糖尿病的病态肥胖人群脂肪组织的胰岛素受体激酶活性。

Diabetes. 1987 May;36(5):620-5. doi: 10.2337/diab.36.5.620.

Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus.肥胖症和2型（非胰岛素依赖型）糖尿病患者骨骼肌中胰岛素受体酪氨酸激酶存在缺陷。

Diabetologia. 1987 Jun;30(6):437-40. doi: 10.1007/BF00292549.

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes.患有和未患非胰岛素依赖型糖尿病的肥胖受试者的人类骨骼肌中的胰岛素受体激酶

J Clin Invest. 1987 May;79(5):1330-7. doi: 10.1172/JCI112958.

Mutations in the insulin receptor gene in genetic forms of insulin resistance.遗传性胰岛素抵抗中胰岛素受体基因的突变。

Recent Prog Horm Res. 1990;46:185-213; discussion 213-7. doi: 10.1016/b978-0-12-571146-3.50011-0.

Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss.非胰岛素依赖型糖尿病中脂肪细胞胰岛素受体激酶活性缺陷的可逆性。体重减轻的影响。

J Clin Invest. 1988 Oct;82(4):1398-406. doi: 10.1172/JCI113744.

Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity.人类骨骼肌胰岛素受体激酶在非胰岛素依赖型糖尿病和肥胖症体内胰岛素抵抗中的作用。

J Clin Endocrinol Metab. 1994 Feb;78(2):471-7. doi: 10.1210/jcem.78.2.8106637.

引用本文的文献

Is type 2 diabetes an adiposity-based metabolic disease? From the origin of insulin resistance to the concept of dysfunctional adipose tissue.2 型糖尿病是一种基于肥胖的代谢性疾病吗？从胰岛素抵抗的起源到功能失调的脂肪组织概念。

Eat Weight Disord. 2021 Dec;26(8):2429-2441. doi: 10.1007/s40519-021-01109-4. Epub 2021 Feb 8.

The K121Q polymorphism in ENPP1 (PC-1) is not associated with type 2 diabetes or obesity in Korean male workers.在韩国男性工人中，ENPP1（PC-1）基因的K121Q多态性与2型糖尿病或肥胖症无关。

J Korean Med Sci. 2008 Jun;23(3):459-64. doi: 10.3346/jkms.2008.23.3.459.

Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle.一氧化氮制剂会损害大鼠骨骼肌中胰岛素介导的信号转导。

BMC Biochem. 2006 May 27;7:17. doi: 10.1186/1471-2091-7-17.

Insulin-induced translocation of GLUT 4 in skeletal muscle of insulin-resistant Zucker rats.胰岛素诱导胰岛素抵抗型 Zucker 大鼠骨骼肌中葡萄糖转运蛋白 4（GLUT 4）的转位。

Diabetologia. 1994 Jan;37(1):3-9. doi: 10.1007/BF00428770.

Lipid-induced insulin resistance in cultured hepatoma cells is associated with a decreased insulin receptor tyrosine kinase activity.培养的肝癌细胞中脂质诱导的胰岛素抵抗与胰岛素受体酪氨酸激酶活性降低有关。

Cell Regul. 1991 Jan;2(1):65-72. doi: 10.1091/mbc.2.1.65.

Alternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissues.胰岛素受体蛋白的可变剪接变体。在正常和糖尿病人类组织中的表达。

J Clin Invest. 1992 Jun;89(6):2066-70. doi: 10.1172/JCI115819.

Differential regulation of multiple hepatic protein tyrosine phosphatases in alloxan diabetic rats.四氧嘧啶糖尿病大鼠中多种肝脏蛋白酪氨酸磷酸酶的差异调节

J Clin Invest. 1992 Jul;90(1):174-9. doi: 10.1172/JCI115833.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验