冠状动脉疾病与冠状动脉周围心外膜脂肪组织厚度之间的关系。
The relationship between coronary artery disease and pericoronary epicardial adipose tissue thickness.
作者信息
Aydın Ayşe Murat, Kayalı Alperen, Poyraz Ahmet Kurşad, Aydın Kemal
机构信息
Department of Radiology, School of Medicine, Fırat University, Elazig, Turkey
Department of Radiology, School of Medicine, Fırat University, Elazig, Turkey.
出版信息
J Int Med Res. 2015 Feb;43(1):17-25. doi: 10.1177/0300060514558323. Epub 2014 Dec 4.
OBJECTIVES
A retrospective study to investigate the relationship between epicardial adipose tissue thickness (EATT) and presence of coronary artery plaque, coronary artery disease (CAD) and CAD risk factors.
METHODS
Multidetector computed tomography (MDCT) coronary angiography images were reviewed. Left anterior decending artery, right coronary artery and left circumflex artery pericoronary EATT were measured. Demographic, clinical and CAD risk factor data were obtained from medical records.
RESULTS
Patients with CAD (n = 49) had significantly larger mean EATT than those without CAD (n = 101). Pericoronary EATT was significantly correlated with body mass index, total cholesterol level, coronary artery calcium score, hypertension and diabetes mellitus history.
CONCLUSIONS
There is an association between pericoronary EATT and CAD, as well as CAD risk factors. Pericoronary EATT measurement may become a widely used, easy-to-perform method for determining CAD risk.
目的
进行一项回顾性研究，以调查心外膜脂肪组织厚度（EATT）与冠状动脉斑块、冠状动脉疾病（CAD）及CAD危险因素之间的关系。
方法
回顾多排螺旋计算机断层扫描（MDCT）冠状动脉造影图像。测量左前降支、右冠状动脉和左旋支冠状动脉周围的EATT。从病历中获取人口统计学、临床和CAD危险因素数据。
结果
CAD患者（n = 49）的平均EATT显著大于无CAD患者（n = 101）。冠状动脉周围EATT与体重指数、总胆固醇水平、冠状动脉钙化积分、高血压和糖尿病病史显著相关。
结论
冠状动脉周围EATT与CAD以及CAD危险因素之间存在关联。冠状动脉周围EATT测量可能成为一种广泛应用、易于实施的确定CAD风险的方法。
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