Shakoor Sadia, Qamar Farah Naz, Mir Fatima, Zaidi Anita, Hasan Rumina
Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Arch Dis Child. 2015 Feb;100(2):198-205. doi: 10.1136/archdischild-2013-304816. Epub 2014 Dec 5.
Paediatric tuberculosis (TB) has long been an evasive entity for public health practitioners striving to control the disease. Owing to difficulty in diagnosis of paediatric TB, incidence estimates based on current case detection fall short of actual rates. The four high-burden countries in South Asia (SA-HBC)-Afghanistan, Pakistan, India and Bangladesh-alone account for >75% of missed TB cases worldwide. It follows that these countries are also responsible for a large although unmeasured proportion of missed paediatric cases. In view of current Millennium Development Goals recommending a scale-up of paediatric TB detection and management globally, there is a dire need to improve paediatric TB programmes in these high-burden countries. Inherent problems with diagnosis of paediatric TB are compounded by programmatic and social barriers in SA-HBC. We have reviewed the current situation of TB control programmes in SA-HBC countries based on published statistics and performed a strengths, weaknesses, opportunities and threats situational analysis with a view towards identifying critical issues operant in the region posing barriers to improving paediatric TB control.
长期以来,对于致力于控制小儿结核病的公共卫生从业者而言,小儿结核病一直是个难以捉摸的问题。由于小儿结核病诊断困难,基于当前病例发现情况的发病率估计低于实际发病率。仅南亚四个高负担国家(阿富汗、巴基斯坦、印度和孟加拉国)就占全球漏诊结核病病例的75%以上。因此,这些国家也应对大量(尽管未测量)漏诊的小儿病例负责。鉴于当前千年发展目标建议在全球范围内扩大小儿结核病的检测和管理,迫切需要改善这些高负担国家的小儿结核病防治项目。南亚高负担国家的规划和社会障碍使小儿结核病诊断的固有问题更加复杂。我们根据已公布的统计数据回顾了南亚高负担国家结核病控制项目的现状,并进行了优势、劣势、机会和威胁态势分析,以期确定该地区存在的阻碍改善小儿结核病控制的关键问题。