Kovalenko T V, Trusov V V, Ametov A S
Pediatriia. 1989(6):54-7.
The secretory activity of C-cells of the thyroid was investigated in 25 children with rickets and rickets-like diseases. There were 13 children with grades II and III rickets, 6 with vitamin D-dependent rickets, and 6 with Debre-de Toni-Fanconi disease. Five normal children constituted a control group. The basal concentration of calcitonin did not differ from the control parameter in all patients' groups. An increased release of the hormone to the blood was noticed in response to calcium stimulation. The rise of blood calcitonin was determined by the disease pattern, which made it possible to use the test with a one-minute intravenous calcium injection for differential diagnosis purposes. The maximal changes were discovered in children suffering from vitamin D-dependent rickets.
对25例患有佝偻病和类佝偻病的儿童的甲状腺C细胞的分泌活性进行了研究。其中13例为II级和III级佝偻病患儿，6例为维生素D依赖性佝偻病患儿，6例为德布雷 - 德托尼 - 范科尼病患儿。5名正常儿童组成一个对照组。所有患者组降钙素的基础浓度与对照参数无差异。在钙刺激后，发现激素向血液中的释放增加。血降钙素的升高取决于疾病类型，这使得可以使用一分钟静脉注射钙试验进行鉴别诊断。在患有维生素D依赖性佝偻病的儿童中发现了最大变化。
