Gnepp D R, Heffner D K
Department of Pathology, St. Louis University, School of Medicine, Missouri.
Mod Pathol. 1989 Jul;2(4):365-71.
One hundred seven sinonasal tract adenomatous neoplasms on file at the Armed Forces Institute of Pathology were reviewed in order to determine what percentage of and what type of nonsquamous epithelial neoplasms arise from surface mucosa. Seventy-seven percent of tumors were localized to the nose or maxillary sinus. Fifty-nine of the 107 tumors (55%) including 32 (50%) of the 64 adenocarcinomas and 19 (59%) of the 31 adenoid cystic carcinomas arose from the surface mucosa. Five of the six mucoepidermoid carcinomas also appeared to arise from the surface in a diffuse fashion, as did both mixed tumors, one of the oncocytic adenomas and the papillary cystadenoma. One can conclude that the majority of sinonasal tract adenomatous neoplasms arise from the mucosal lining of the sinonasal tract.
为了确定非鳞状上皮肿瘤起源于表面黏膜的比例及类型,我们回顾了存档于武装部队病理研究所的107例鼻窦腺瘤性肿瘤。77%的肿瘤局限于鼻腔或上颌窦。107例肿瘤中的59例(55%),包括64例腺癌中的32例(50%)和31例腺样囊性癌中的19例(59%)起源于表面黏膜。6例黏液表皮样癌中的5例以及混合瘤、1例嗜酸性细胞腺瘤和乳头状囊腺瘤似乎也以弥漫方式起源于表面。可以得出结论,大多数鼻窦腺瘤性肿瘤起源于鼻窦的黏膜内衬。