Department of Otolaryngology - Head and Neck Surgery, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Neurosurg Clin N Am. 2013 Jan;24(1):39-49. doi: 10.1016/j.nec.2012.08.004. Epub 2012 Sep 10.
Sinonasal carcinomas are uncommon neoplasms accounting for approximately 3% to 5% of all upper respiratory tract malignancies. Sinonasal malignancies in most cases do not cause early symptoms and present in an advanced stage of disease. Exact staging necessitates a clinical and endoscopic examination with biopsy and imaging. Tumor resection using an open or endoscopic approach is usually considered the first treatment option. In general, sinonasal carcinomas are radiosensitive, so adjuvant or neoadjuvant radiation treatment may be indicated in advanced disease. Multidisciplinary surgical and medical oncologic approaches, including ablation and reconstruction, have enhanced the survival outcome over the past few decades.
鼻窦癌是一种罕见的肿瘤，约占所有上呼吸道恶性肿瘤的 3%至 5%。大多数情况下，鼻窦恶性肿瘤不会引起早期症状，而是在疾病的晚期出现。准确分期需要进行临床和内镜检查，并进行活检和影像学检查。使用开放式或内镜式手术切除肿瘤通常被认为是首选的治疗方法。一般来说，鼻窦癌对放射治疗敏感，因此在晚期疾病中可能需要辅助或新辅助放射治疗。过去几十年，包括消融和重建在内的多学科手术和肿瘤内科治疗方法提高了生存率。
