Shigefuku Ryuta, Takahashi Hideaki, Tsuda Takashi, Ikeda Hiroki, Matsunaga Kotaro, Matsumoto Nobuyuki, Okuse Chiaki, Boku Narikazu, Itoh Fumio, Suzuki Michihiro
Department of Gastroenterology and Hepatology, St. Marianna University School of Medicine.
Nihon Shokakibyo Gakkai Zasshi. 2014 Dec;111(12):2326-36.
Some cases of portal hypertension developing during the course of oxaliplatin-based chemotherapy have been reported. However, there have been no reports of rupture of esophagogastric varices (EGV) in Japan. We present two cases of rupture of EGV during the course of oxaliplatin-based chemotherapy. One case was treated via balloon-occluded retrograde transvenous obliteration, and the other case was treated by using endoscopic variceal ligation and endoscopic injection sclerotherapy. On the basis of our results, we recommend careful monitoring for the occurrence of EGV during the course of oxaliplatin-based chemotherapy.
已有报告称，在基于奥沙利铂的化疗过程中会出现一些门静脉高压病例。然而，在日本尚无食管胃静脉曲张（EGV）破裂的报告。我们报告了两例在基于奥沙利铂的化疗过程中发生EGV破裂的病例。一例通过球囊闭塞逆行静脉栓塞术治疗，另一例采用内镜下静脉曲张结扎术和内镜注射硬化疗法治疗。根据我们的结果，我们建议在基于奥沙利铂的化疗过程中密切监测EGV的发生情况。
