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重塑转录回路:微生物如何适应在人体中定殖。

Reshuffling transcriptional circuits: how microorganisms adapt to colonize the human body.

作者信息

De Sonakshi, Pérez J Christian

机构信息

a Institut für Molekulare Infektionsbiologie ; Universität Würzburg ; Würzburg , Germany.

出版信息

Transcription. 2014;5(5):e976095. doi: 10.4161/21541264.2014.976095. Epub 2014 Dec 17.

Abstract

Several hundred taxa of microorganisms-including bacteria, archaea and eukaryotes-inhabit the human body. What did it take for these species to become stable residents of humans? Recent reports illustrate how evolutionary changes in transcriptional circuits played a pivotal role in the adaptation of single-celled eukaryotes to colonize mammals.

摘要

包括细菌、古细菌和真核生物在内的数百种微生物类群栖息在人体中。这些物种是如何成为人类的稳定寄居者的呢?最近的报告说明了转录回路的进化变化是如何在单细胞真核生物适应定殖于哺乳动物的过程中发挥关键作用的。

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