Corbel D, Guilloteau D, Itti R
Bull Acad Natl Med. 1989 Feb;173(2):223-7.
The dermis, considered as a potential route of administration for drugs, has been widely and empirically used for more than a century. The comparative intravenous and intradermal administration of radiotracers makes it possible to demonstrate that the intradermal route has its own diffusion kinetics and its own biodistribution.
真皮被视为药物的一种潜在给药途径,在一个多世纪以来一直被广泛且经验性地使用。放射性示踪剂的静脉注射和皮内注射对比给药使得证明皮内途径具有其自身的扩散动力学和生物分布成为可能。