Yuanyuan Mi, Ning Shao, Yang Wang, Xiaoming You, Lijie Zhu, Ninghan Feng
Department of Urology, Third Affiliated Hospital of Nantong University, Wuxi, China.
Cell Biochem Biophys. 2015 Mar;71(2):1117-21. doi: 10.1007/s12013-014-0316-7.
Peyronie's disease (PD) is marked by severe penile curved deformity and/or abnormal sexual function. The study aim was to determine the clinical efficacy of a new surgical procedure for PD, aimed at restoration of normal erection and improvement of the coital function. For this purpose, 5 cases of PD with erectile pain and curved deformity, aged 26-49 (median: 37.2) years, who previously underwent penile induration resection and autologous testicular tunica vaginalis patch grafting were retrospectively analyzed to determine the clinical efficacy of the treatment and impact on the postoperative sexual function. After follow-up for more than 12 months, all patients experienced normal penile erection without the erectile pain, and they were all fully satisfied with their sexual performance. No testicular atrophy, torsion, or necrosis of the operative side was observed. The curved deformity while penile erection was satisfactorily corrected, and the 4 out of 5 (80 %) cases displayed completely normal appearance of the penile erection. However, the remaining one case experienced local slake and bulging of the repair site while penile erection. We, therefore, concluded that the testicular tunica vaginalis patch grafting was a safe, convenient, economical, and effective procedure for the treatment of PD.
佩罗尼氏病（PD）的特征是严重的阴茎弯曲畸形和/或性功能异常。本研究的目的是确定一种针对PD的新手术方法的临床疗效，旨在恢复正常勃起并改善性交功能。为此，回顾性分析了5例年龄在26 - 49岁（中位数：37.2岁）、患有勃起疼痛和弯曲畸形的PD患者，这些患者此前接受了阴茎硬结切除术和自体睾丸鞘膜补片移植，以确定该治疗方法的临床疗效及其对术后性功能的影响。经过超过12个月的随访，所有患者阴茎勃起正常，无勃起疼痛，且对其性功能均非常满意。未观察到手术侧睾丸萎缩、扭转或坏死。阴茎勃起时的弯曲畸形得到了满意矫正，5例中有4例（80%）阴茎勃起外观完全正常。然而，其余1例在阴茎勃起时修复部位出现局部松弛和隆起。因此，我们得出结论，睾丸鞘膜补片移植是一种治疗PD的安全、便捷、经济且有效的方法。
