Klijanienko Jerzy, Pierron Gaelle, Sastre-Garau Xavier, Theocharis Stamatios
Department of Tumor Biology, Curie Institute, Paris, France.
Cancer Cytopathol. 2015 Mar;123(3):141-51. doi: 10.1002/cncy.21496. Epub 2014 Dec 8.
The diagnosis of a soft tissue tumor (STT) is a complex process that requires a multidisciplinary team consisting of a medical oncologist, a radiologist, a pathologist, and a molecular biologist. The combination of this information gives highly accurate results. Fine-needle aspiration in this setting is one of the most performed techniques for obtaining, in a noninvasive way, optimal material for morphological, immunohistochemical, and molecular purposes. On the other hand, an accurate tumor diagnosis is a dynamic process, as evidenced by the constant modifications of international putative classifications, which are more and more based on molecular aberrations (2013 World Health Organization classification). In the future, STT classification will certainly be a hybrid of morphology and molecular data and, consequently, will be very "useful" for cytology.
软组织肿瘤（STT）的诊断是一个复杂的过程，需要由医学肿瘤学家、放射科医生、病理学家和分子生物学家组成的多学科团队。这些信息的结合能得出高度准确的结果。在这种情况下，细针穿刺是最常用的技术之一，它能以非侵入性方式获取用于形态学、免疫组织化学和分子检测的最佳材料。另一方面，准确的肿瘤诊断是一个动态过程，国际公认分类的不断修订就证明了这一点，这些分类越来越多地基于分子异常（2013年世界卫生组织分类）。未来，STT分类肯定会是形态学和分子数据的结合，因此，对细胞学将非常“有用”。
