Demartini B, Ricciardi L, Parees I, Ganos C, Bhatia K P, Edwards M J
Sobell Department, UCL Institute of Neurology, London, UK; Department of Psychiatry, San Paolo Hospital and University of Milan, Milan, Italy.
Eur J Neurol. 2015 Mar;22(3):527-e36. doi: 10.1111/ene.12609. Epub 2014 Dec 9.
Functional tics, also called psychogenic tics or pseudo-tics, are difficult to diagnose because of the lack of diagnostic criteria and their clinical similarities to organic tics. The aim of the present study was to report a case series of patients with documented functional tics and to describe their clinical characteristics, risk factors and psychiatric comorbidity. Also clinical tips are suggested which might help the differential diagnosis in clinical practice.
Eleven patients (mean age at onset 37.2, SD 13.5; three females) were included with a documented or clinically established diagnosis of functional tics, according to consultant neurologists who have specific expertise in functional movement disorders or in tic disorders. Adult onset, absent family history of tics, inability to suppress the movements, lack of premonitory sensations, absence of pali-, echo- and copro-phenomena, presence of blocking tics, the lack of the typical rostrocaudal tic distribution and the coexistence of other functional movement disorders were common in our patients.
Our data suggest that functional tics can be differentiated from organic tics on clinical grounds, although it is also accepted that this distinction can be difficult in certain cases. Clinical clues from history and examination described here might help to identify patients with functional tics.
功能性抽动,也称为心理性抽动或假性抽动,由于缺乏诊断标准且在临床上与器质性抽动相似,因此难以诊断。本研究的目的是报告一系列有记录的功能性抽动患者病例,并描述其临床特征、危险因素和精神共病情况。此外,还提出了一些临床提示,可能有助于临床实践中的鉴别诊断。
根据在功能性运动障碍或抽动障碍方面具有专业专长的神经科顾问医生的诊断,纳入了11例患者(发病时平均年龄37.2岁,标准差13.5;3名女性),他们被诊断为有记录的或临床上确诊的功能性抽动。成年起病、无抽动家族史、无法抑制动作、无前兆感觉、无重复动作、模仿动作和秽语现象、存在阻断性抽动、缺乏典型的头尾向抽动分布以及合并其他功能性运动障碍在我们的患者中很常见。
我们的数据表明,尽管在某些情况下也公认这种区分可能困难,但功能性抽动在临床上可以与器质性抽动相鉴别。这里描述的病史和检查中的临床线索可能有助于识别功能性抽动患者。