Roberts J K, Korones G K, Levine H L, Wood B G, Tucker H M, Lavertu P
Cleve Clin J Med. 1989 Jul-Aug;56(5):529-33. doi: 10.3949/ccjm.56.5.529.
During 1977 through 1986, 15 patients were evaluated and underwent surgery for nasopharyngeal angiofibroma at the Cleveland Clinic Foundation. All were males aged five to 20 years. Diagnoses were established clinically and radiographically. The most common presentations were nasal obstruction and epistaxis. Computed tomographic scans were obtained in almost all cases. In 14 patients, preoperative embolization of the tumor was performed at the time of diagnostic angiography; embolization of tumors made surgical excision easier and reduced blood loss. The most common surgical exposure used was a combination of transpalatal and transantral approaches. Follow-up of one to 10 years showed recurrence in only two patients. One had no further recurrence after subsequent surgery; the other remains asymptomatic with no further progression. The approach to diagnosis and treatment described results in cure for most patients.
1977年至1986年间，克利夫兰诊所基金会对15例鼻咽血管纤维瘤患者进行了评估并实施了手术。所有患者均为5至20岁的男性。通过临床和影像学检查确诊。最常见的症状是鼻塞和鼻出血。几乎所有病例均进行了计算机断层扫描。14例患者在诊断性血管造影时进行了术前肿瘤栓塞；肿瘤栓塞使手术切除更容易并减少了失血。最常用的手术入路是经腭和经窦联合入路。1至10年的随访显示仅2例患者复发。1例患者后续手术后未再复发；另1例患者无症状且病情无进一步进展。所描述的诊断和治疗方法可使大多数患者治愈。
