Awais Muhammad, Rehman Abdul, Baloch Noor Ul-Ain, Khan Farid, Khan Naseer
Department of Radiology, Aga Khan University Hospital, P.O. box 3500, Stadium Road, Karachi 74800, Sindh, Pakistan.
Expert Rev Anti Infect Ther. 2015 Feb;13(2):209-31. doi: 10.1586/14787210.2015.991717. Epub 2014 Dec 9.
Urinary tract infections (UTIs) represent an important cause of febrile illness in young children and can lead to renal scarring and kidney failure. However, diagnosis and treatment of recurrent UTI in children is an area of some controversy. Guidelines from the American Academy of Pediatrics, National Institute for Health and Clinical Excellence and European Society of Paediatric Radiology differ from each other in terms of the diagnostic algorithm to be followed. Treatment of vesicoureteral reflux and antibiotic prophylaxis for prevention of recurrent UTI are also areas of considerable debate. In this review, we collate and appraise recently published literature in order to formulate evidence-based guidance for the diagnosis and treatment of recurrent UTI in children.
尿路感染（UTIs）是幼儿发热性疾病的一个重要原因，可导致肾瘢痕形成和肾衰竭。然而，儿童复发性尿路感染的诊断和治疗是一个存在一些争议的领域。美国儿科学会、国家卫生与临床优化研究所和欧洲儿科放射学会的指南在应遵循的诊断算法方面存在差异。膀胱输尿管反流的治疗以及预防复发性尿路感染的抗生素预防也是备受争议的领域。在本综述中，我们整理并评估最近发表的文献，以便为儿童复发性尿路感染的诊断和治疗制定循证指南。
