Cherniavskiĭ A M, Volkov A M, Lavreniuk O V, Terekhov I N, Kareva Iu E
Angiol Sosud Khir. 2014;20(4):130-6.
comparative assessment of endoscopic and open exposure of the great saphenous vein during the operation of coronary artery bypass grafting.
a total of 228 patients with endured coronary artery bypass graft operation were randomized depending on the method of exposing the great saphenous vein (GSV) - an open method of vein exposure (OVE) - 115 patients and endoscopic vein exposure (EVE) - 113 patients. The evaluated parameters included healing of the postoperative wounds, postoperative oedema, pain intensity, and neuropathies in the early postoperative period. We performed lymphoscintigraphy of the lower limbs, as well as morphological examination of the venous wall by means of light and electron scanning microscopy.
the duration of vein exposure was less in the EVE group than in the OVE group, amounting to 31.8 ± 6.2 min and 40.3 ± 15.8 min, respectively (p<0.01). Complications after GSV isolation were encountered considerably less often in the EVE group (11.5%) as compared to 44.4% in the OVE (p=0.001). According to the results of the multivariate analysis, diabetes mellitus was the only risk factor for postoperative complications in OVE. According the findings of lymphoscintigraphy the EVE group had no significant impairments of lymph outflow after the operation, whereas during OVE, accumulation of radiopaque material in the lymph nodes decreased twofold (p ≤ 0.001). Histological assessment of the sampled vein specimens showed no considerable lesions of the venous wall in the examined groups.
the obtained findings confirm high efficacy of using EVE during operations of CABG, lower traumaticity of this method with a conduit of good quality, which was proven based on electron microscopy of the vein fragments.
冠状动脉搭桥手术中内镜下与开放方式显露大隐静脉的对比评估。
总共228例接受冠状动脉搭桥手术的患者,根据显露大隐静脉(GSV)的方法进行随机分组——开放静脉显露法(OVE)——115例患者,内镜静脉显露法(EVE)——113例患者。评估参数包括术后伤口愈合情况、术后水肿、疼痛强度以及术后早期的神经病变。我们对下肢进行了淋巴闪烁显像检查,并通过光镜和电子扫描显微镜对静脉壁进行了形态学检查。
EVE组静脉显露时间短于OVE组,分别为31.8±6.2分钟和40.3±15.8分钟(p<0.01)。与OVE组的44.4%相比,EVE组在GSV分离后并发症的发生率明显更低(11.5%)(p = 0.001)。根据多变量分析结果,糖尿病是OVE术后并发症的唯一危险因素。根据淋巴闪烁显像检查结果,EVE组术后淋巴流出无明显受损,而在OVE术中,淋巴结中不透射线物质的积聚减少了两倍(p≤0.001)。对所取静脉标本的组织学评估显示,在所检查的组中静脉壁无明显病变。
所得结果证实了在冠状动脉搭桥手术中使用EVE的高效性,该方法创伤性较小且能获取质量良好的血管,这已通过静脉片段的电子显微镜检查得到证实。