Bibikov N G
Zh Evol Biokhim Fiziol. 2013 Nov-Dec;49(6):417-27.
Firing activity of 104 neurons located on the medullar dorsal nucleus (a homolog of the complex of mammalian cochlear nuclei) of immobilized common frogs (Rana temporaria) was recorded extracellularly in the absence of external auditory signals. This background activity was analyzed by using the stochastic point process characteristics, such as the variation coefficient, local coefficient of variation, interdependence of the next intervals, the interpulse interval distribution, autocorrelation, and hazard function. All these parameters were compared with the relative number of the interpulse intervals included in bursts ("bursting") that are determined by the offered technique. In neurons with the expressed refractoriness the bursting usually was lower, whereas in neurons with expressed maximum of the correlation function--higher than in the casual Poisson process. However, even in the last group of cells the number of intervals included in bursts was not decreased after casual shuffling of all interpulse intervals. As a result, we have failed to observe any real bursting background activity in the secondary order auditory neurons of the studied amphibian species. The data are compared with features of the background firing in different nuclei of the mammalian auditory pathway.
在没有外部听觉信号的情况下，对固定的普通青蛙（林蛙）延髓背核（哺乳动物耳蜗核复合体的同源物）上的104个神经元的放电活动进行了细胞外记录。利用随机点过程特征，如变异系数、局部变异系数、相邻间隔的相互依赖性、脉冲间隔分布、自相关和风险函数，对这种背景活动进行了分析。将所有这些参数与由所提供技术确定的爆发中包含的脉冲间隔的相对数量（“爆发”）进行了比较。在具有明显不应期的神经元中，爆发通常较低，而在具有相关函数最大值的神经元中——高于随机泊松过程。然而，即使在最后一组细胞中，在所有脉冲间隔随机洗牌后，爆发中包含的间隔数量也没有减少。结果，我们未能在所研究的两栖类物种的二级听觉神经元中观察到任何真正的爆发性背景活动。将这些数据与哺乳动物听觉通路不同核团的背景放电特征进行了比较。
