Drexel University, Radiation Oncology, Medical Physics.
J Appl Clin Med Phys. 2014 Nov 8;15(6):4575. doi: 10.1120/jacmp.v15i6.4575.
We examined the adequacy of existing shielding guidelines using five-year clinical data from a busy CyberKnife center. From June 2006 through July 2011, 1,370 patients were treated with a total of 4,900 fractions and 680,691 radiation beams using a G4 CyberKnife. Prescription dose and total monitor units (MU) were analyzed to estimate the shielding workload and modulation factor. In addition, based on the beam's radiation source position, targeting position, MU, and beam collimator size, the MATLAB program was used to project each beam toward the shielding barrier. The summation of the projections evaluates the distribution of the shielding load. On average, each patient received 3.6 fractions, with an average 9.1 Gy per fraction prescribed at the 71.1% isodose line, using 133.7 beams and 6,200 MU. Intracranial patients received an average of 2.7 fractions, with 8.6 Gy per fraction prescribed at the 71.4% isodose line, using 133 beams and 5,083 MU. Extracranial patients received an average of 3.94 fractions, with 9.2 Gy per frac- tion prescribed at the 71% isodose line, using 134 beams and 6,514 MU. Most- used collimator sizes for intracranial patients were smaller (7.5 to 20 mm) than for extracranial patients (20 to 40 mm). Eighty-five percent of the beams exited through the floor, and about 40% of the surrounding wall area received no direct beam. For the rest of the wall, we found "hot" areas that received above-average MU. The locations of these areas were correlated with the projection of the nodes for extracranial treatments. In comparison, the beam projections on the wall were more spread for intracranial treatments. The maximum MU any area received from intracranial treatment was less than 0.25% of total MU used for intracranial treatments, and was less than 1.2% of total MU used for extracranial treatments. The combination of workload, modulation factor, and use factor in our practice are about tenfold less than recommendations in the existing CyberKnife shielding guidelines. The current guidelines were found to be adequate for shielding, even in a busy center. There may be a potential to reduce shielding in areas with no or few direct beams in the current G4 model. Since a newer model CyberKnife (M6) has recently been introduced, the patterns of usage reported here may be changed in the future. The uneven distribution of use factor we have found may, however, be considered in the vault design.
我们使用一个繁忙的 CyberKnife 中心的五年临床数据来检查现有的屏蔽指南是否充分。从 2006 年 6 月至 2011 年 7 月,共有 1370 名患者接受了治疗,共进行了 4900 次分次和 680691 次射线束照射,使用了 G4 CyberKnife。分析了处方剂量和总监测单位 (MU),以估计屏蔽工作量和调制因数。此外,根据射束的辐射源位置、靶位置、MU 和射束准直器尺寸,使用 MATLAB 程序将每个射束投射到屏蔽壁上。投影的总和评估屏蔽负载的分布。平均而言,每位患者接受 3.6 次分次治疗,每次治疗的平均处方剂量为 71.1%等剂量线的 9.1Gy,使用 133.7 束和 6200MU。颅内患者平均接受 2.7 次分次治疗,每次治疗的平均处方剂量为 71.4%等剂量线的 8.6Gy,使用 133 束和 5083MU。颅外患者平均接受 3.94 次分次治疗,每次治疗的平均处方剂量为 71%等剂量线的 9.2Gy,使用 134 束和 6514MU。颅内患者最常使用的准直器尺寸较小(7.5 至 20mm),而颅外患者的准直器尺寸较大(20 至 40mm)。85%的射束从地板逸出,约 40%的周围墙壁区域没有直接射束。对于其余的墙壁,我们发现“热点”区域接收的 MU 高于平均水平。这些区域的位置与颅外治疗的节点投影相关。相比之下,颅内治疗的射束在墙上的投影更为分散。任何区域从颅内治疗中接收的最大 MU 都小于颅内治疗中使用的总 MU 的 0.25%,也小于颅外治疗中使用的总 MU 的 1.2%。我们实践中的工作量、调制因数和使用因数的组合比现有 CyberKnife 屏蔽指南中的建议少十倍左右。即使在繁忙的中心,现有的指南也被发现足以进行屏蔽。在当前的 G4 模型中,可能有机会减少无直接射束或直接射束较少的区域的屏蔽。由于最近推出了一种新型 CyberKnife(M6),因此这里报告的使用模式可能会在未来发生变化。我们发现的使用因数分布不均,然而,在拱顶设计中可以考虑这一点。