Abdulmajed Mohamed Ismat, Hughes Daniel, Shergill Iqbal Singh
Wrexham Maelor Hospital, Croesnewydd Road, Wrexham, Wales, LL13 7TD, UK.
Expert Rev Med Devices. 2015 Mar;12(2):175-82. doi: 10.1586/17434440.2015.990376. Epub 2014 Dec 11.
The incidence of prostate cancer has shown a significant increase, highlighting the importance of early diagnosis. Current practice considers histological diagnosis a necessity in the majority of the cases. The limitations of transrectal biopsies led to the development of the promising transperineal prostatic biopsies. The latter offers a safer approach by avoiding the rectum, utilizing brachytherapy template grid to detect anterior zone disease and provides accurate prostatic mapping by systematically sampling the whole gland. It also helps to direct biopsies based on images obtained from previous prostate scanning and identify those eligible for focal therapy to direct focal treatment accurately. The current literature provides enough reassurance that transperineal template biopsies are effective, efficient and superior to the traditional and inaccurate transrectal biopsies. The absence of consensus on the technical aspect of template biopsies is a drawback, yet it highlights the need to develop robust guidelines to standardize the procedure.
前列腺癌的发病率显著上升,凸显了早期诊断的重要性。目前的做法认为,在大多数情况下,组织学诊断是必要的。经直肠活检的局限性促使了前景广阔的经会阴前列腺活检的发展。后者通过避开直肠提供了一种更安全的方法,利用近距离放射治疗模板网格来检测前区疾病,并通过对整个腺体进行系统采样来提供准确的前列腺定位。它还有助于根据先前前列腺扫描获得的图像指导活检,并确定那些适合聚焦治疗的患者,从而准确地指导聚焦治疗。当前的文献充分表明,经会阴模板活检是有效、高效的,且优于传统的、不准确的经直肠活检。在模板活检的技术方面缺乏共识是一个缺点,但它凸显了制定强有力的指南以规范该程序的必要性。