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低剂量阿霉素和长春地辛诱发的致死性急性间质性肺炎。

Fatal acute interstitial pneumonia induced by low-dose doxorubicin and vindesine.

作者信息

Isawa T, Ono R, Motomiya M, Tamahashi N

机构信息

Department of Medicine, Tohoku University, Sendai, Japan.

出版信息

Tohoku J Exp Med. 1989 Jun;158(2):149-54. doi: 10.1620/tjem.158.149.

Abstract

A 53-year-old female smoker with small cell carcinoma of the lung with cerebral metastases was initially treated with whole brain radiation with favorable responses. She developed fulminant and fatal interstitial pneumonia following administration of 30 mg of doxorubicin and 6 mg of vindesine. Histopathology revealed that the interstitial pneumonia was compatible with a drug-induced pneumonia.

摘要

一名53岁的吸烟女性,患有小细胞肺癌并伴有脑转移,最初接受了全脑放疗,反应良好。在给予30毫克阿霉素和6毫克长春地辛后,她患上了暴发性致命性间质性肺炎。组织病理学显示,间质性肺炎与药物性肺炎相符。

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