脊髓灰质炎病毒原衣壳的变性
Denaturation of poliovirus procapsids.
作者信息
Rombaut B, Vrijsen R, Boeyé A
机构信息
Department of Microbiology and Hygiene, Vrije Universiteit Brussel, Belgium.
出版信息
Arch Virol. 1989;106(3-4):213-20. doi: 10.1007/BF01313954.
PMID:2549918
Abstract
The denaturation of poliovirus procapsids at pH 6.5 was studied, both in the frozen and liquid condition. Denaturation involved alteration of antigenic and physical features (isoelectric pH, alkali dissociability, sedimentation coefficient). Magnesium was a stabilizing factor, and the sedimentation coefficient was the most denaturation-sensitive feature.
摘要
研究了脊髓灰质炎病毒原衣壳在pH 6.5条件下，在冷冻和液体状态下的变性情况。变性涉及抗原和物理特性（等电pH值、碱解离性、沉降系数）的改变。镁是一种稳定因素，沉降系数是对变性最敏感的特性。
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