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机器人辅助腹腔镜下剖宫产瘢痕妊娠病灶切除术及子宫切口修复术

Robotic-assisted laparoscopic removal of cesarean scar ectopic and hysterotomy revision.

作者信息

Siedhoff Matthew T, Schiff Lauren D, Moulder Janelle K, Toubia Tarek, Ivester Thomas

机构信息

Advanced Laparoscopy and Pelvic Pain, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC.

Advanced Laparoscopy and Pelvic Pain, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC.

出版信息

Am J Obstet Gynecol. 2015 May;212(5):681.e1-4. doi: 10.1016/j.ajog.2014.12.004. Epub 2014 Dec 10.

Abstract

A 38-year-old gravida 6 para 2042 woman presented in consultation regarding management of a uterine defect, or "niche," following resolution of a cesarean scar ectopic pregnancy. She had 3 prior losses, followed by in vitro fertilization that resulted in 2 healthy births, both delivered by cesarean. A third in vitro embryo transfer resulted in the cesarean scar ectopic. After consideration of treatment options, she underwent multiple-dose parenteral methotrexate with eventual termination of the ectopic. Magnetic resonance imaging demonstrated a uterine defect, suspected to contain residual pregnancy tissue. Questions considered in her consultation included whether the defect should be repaired and, if so, from a hysteroscopic or laparoscopic approach, as well as her risk of intrauterine scarring, when, or if, it would be safe to pursue another pregnancy, and her subsequent risk of uterine rupture. Literature review regarding cesarean niche was helpful, but did not seem to completely inform this particular clinical scenario. She elected to proceed with robotic-assisted laparoscopic repair. The vesicovaginal space was opened to expose the defect. Dilute vasopressin was injected circumferentially around the defect to help minimize the use of electrosurgery in opening the hysterotomy. Scar overlying the defect was resected and pregnancy tissue removed. The hysterotomy was closed with delayed-absorbable barbed suture, extrapolating technique from laparoscopic myomectomy. The first layer was imbricated with a second, similar to a 2-layer closure in cesarean delivery. Follow-up magnetic resonance imaging revealed resolution of the defect. After several failed attempts at repeat in vitro fertilization, spontaneous pregnancy was achieved 18 months postoperatively. The pregnancy was uncomplicated and she underwent scheduled cesarean delivery of a healthy neonate at 37 weeks' gestation. The lower uterine segment was thick and developed, with no evidence of a dehiscence.

摘要

一名38岁、孕6产2042的女性前来咨询剖宫产瘢痕部位异位妊娠治愈后子宫缺损(即“憩室”)的处理方法。她之前有过3次流产,之后通过体外受精成功诞下2名健康婴儿,均为剖宫产。第三次体外胚胎移植导致剖宫产瘢痕部位异位妊娠。在考虑了各种治疗方案后,她接受了多剂量的胃肠外甲氨蝶呤治疗,最终异位妊娠终止。磁共振成像显示子宫存在缺损,怀疑有残留妊娠组织。会诊时考虑的问题包括是否应修复该缺损,如果是,应采用宫腔镜还是腹腔镜手术方式,以及她发生子宫内瘢痕形成的风险、再次怀孕是否安全以及后续子宫破裂的风险。关于剖宫产憩室的文献回顾有所帮助,但似乎并未完全适用于这一特殊临床情况。她选择进行机器人辅助腹腔镜修复手术。打开膀胱阴道间隙以暴露缺损部位。在缺损周围环形注射稀释的血管加压素,以尽量减少在打开子宫切口时使用电外科手术。切除覆盖在缺损上的瘢痕并清除妊娠组织。借鉴腹腔镜子宫肌瘤切除术的技术,用延迟吸收的倒刺缝线关闭子宫切口。第一层与第二层相互覆盖,类似于剖宫产手术中的两层缝合。后续的磁共振成像显示缺损已消失。在多次重复体外受精尝试失败后,术后18个月自然受孕。此次妊娠过程顺利,她在妊娠37周时接受了计划性剖宫产,产下一名健康的新生儿。子宫下段增厚且发育良好,没有裂开的迹象。

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