一名老年帕金森病患者使用普拉克索缓释片后出现听觉音乐幻觉
Auditory musical hallucinations associated with extended-release pramipexole in an elderly patient with Parkinson's disease.
作者信息
Kataoka Hiroshi, Ueno Satoshi
机构信息
From the Department of Neurology, Nara Medical University, Kashihara, Nara, Japan (HK, SU).
出版信息
Medicine (Baltimore). 2014 Dec;93(27):e251. doi: 10.1097/MD.0000000000000251.
Auditory musical hallucinations (AMHs) are rare complex auditory hallucinations in Parkinson's disease (PD) that have been limited previously. The characteristics of AMHs in PD remain uncertain. We describe a 72-year-old woman with PD who presented with AMHs. The AMHs occurred after immediate-release pramipexole was switched to extended-release pramipexole. The AMHs were a quiet piano or often songs on a loud radio or background music over other sounds. The music was unpleasant, but not objectionable, threatening, or ego-syntonic, and it did not interrupt her daily activities. AMHs in PD were non-threatening, and dopaminergic treatment may predispose patients to AMHs or be a unique possible cause of AMHs. The hallucinations can occur after immediate-release pramipexole was switched to extended-release pramipexole.
听觉性音乐幻觉（AMHs）是帕金森病（PD）中罕见的复杂听觉幻觉，此前相关研究有限。PD中AMHs的特征仍不明确。我们描述了一名72岁患有PD的女性，她出现了AMHs。AMHs是在速释普拉克索换成缓释普拉克索后出现的。AMHs表现为安静的钢琴声，或者经常是大声收音机里的歌曲或其他声音之上的背景音乐。这些音乐令人不悦，但并不令人反感、构成威胁或与自我一致，并且没有干扰她的日常活动。PD中的AMHs并无威胁性，多巴胺能治疗可能使患者易患AMHs，或者是AMHs一种独特的可能病因。幻觉可能在速释普拉克索换成缓释普拉克索后出现。
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