电能介导的DNA与聚赖氨酸的动态组装

Dynamic assembly of DNA and polylysine mediated by electric energy.

作者信息

Niu Lin, Yang Xuyan, Zhu Xiaocui, Yin Yudan, Qu Wei, Zhou Jihan, Zhao Meiping, Liang Dehai

机构信息

Beijing National Laboratory for Molecular Sciences and the Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.

出版信息

Chem Commun (Camb). 2015 Jan 28;51(8):1506-9. doi: 10.1039/c4cc07537d.

DOI:10.1039/c4cc07537d

PMID:25501570

Abstract

Under an electric field, the complexes formed by DNA and polylysine exhibit novel features, such as selective merging of particles, ejecting of daughter vehicles, and differentiation of particles of varying mobility. The mobility of the complex could be three times faster than that of free DNA.

摘要

在电场作用下，由DNA和聚赖氨酸形成的复合物呈现出新颖的特性，例如颗粒的选择性合并、子载体的排出以及不同迁移率颗粒的分化。该复合物的迁移率可能比游离DNA快三倍。