Imai Norio, Endo Naoto, Hoshino Tadashi, Suda Ken, Miyasaka Dai, Ito Tomoyuki
Department of Orthopaedic Surgery, Ojiya General Hospital, 1-13-33 Honcho, Ojiya, Niigata, 9478601, Japan.
Department of Orthopaedic Surgery, Niigata University Medical and Dental Hospital, 1-757 Asahimachidori, Niigata, Niigata, Japan.
J Bone Miner Metab. 2016 Jan;34(1):51-4. doi: 10.1007/s00774-014-0640-4. Epub 2014 Dec 14.
Due to the increasing elderly population, the prevalence of osteoporotic hip fractures in Japanese patients continues to rise. It is well established that patients with either hip fracture or both symptomatic and asymptomatic morphometric vertebral compression fracture (VCF) have a poor health prognosis compared with the general population. The purpose of this study was to retrospectively investigate vertebral fracture rates among patients with hip fracture and their influence on mortality. We examined 182 cases of osteoporotic hip fracture in patients admitted to our institution between January 2009 and May 2011. The average age at the time of fracture was 85 years. Radiographs of the lumbar spine were obtained from all of the participants and the lateral spinal radiographs were examined for evidence of VCF. The patients were classified into two groups, those with VCF and those without. A VCF was identified in approximately 78 % of the patients. The mortality rate 1 year after the hip fracture was approximately 22 % and it was significantly higher in patients with VCF. Through multivariate statistics we found that VCF, post-operative complication, loss of ambulation after operation and medication for osteoporosis were statistically significant. In other words, VCF, post-operative complication and loss of ambulation were considered to be poor prognostic factors and medication for osteoporosis was likely to improve the prognosis. We concluded that the risk of mortality after hip fracture is significantly greater in patients who also have VCF compared to patients without VCF, and that medication for osteoporosis is likely to improve prognosis.
由于老年人口不断增加,日本患者骨质疏松性髋部骨折的患病率持续上升。众所周知,与普通人群相比,髋部骨折患者以及有症状和无症状形态计量学椎体压缩骨折(VCF)的患者健康预后较差。本研究的目的是回顾性调查髋部骨折患者的椎体骨折发生率及其对死亡率的影响。我们检查了2009年1月至2011年5月期间入住我院的182例骨质疏松性髋部骨折患者。骨折时的平均年龄为85岁。所有参与者均拍摄了腰椎X线片,并检查了脊柱侧位X线片以寻找VCF的证据。患者被分为两组,有VCF组和无VCF组。约78%的患者被发现有VCF。髋部骨折后1年的死亡率约为22%,有VCF的患者死亡率显著更高。通过多变量统计分析,我们发现VCF、术后并发症、术后行走能力丧失和骨质疏松症用药具有统计学意义。换句话说,VCF、术后并发症和行走能力丧失被认为是不良预后因素,而骨质疏松症用药可能会改善预后。我们得出结论,与无VCF的患者相比,同时患有VCF的髋部骨折患者死亡风险显著更高,并且骨质疏松症用药可能会改善预后。