Heschl S, Colantonio C, Pieske B, Toller W
Universitätsklinik für Anästhesiologie und Intensivmedizin, Klin. Abteilung für Herz-, Thorax-, Gefäßchirurgische Anästhesiologie und Intensivmedizin, Medizinische Universität Graz, Auenbruggerplatz 29, 8036, Graz, Österreich,
Anaesthesist. 2014 Dec;63(12):951-7. doi: 10.1007/s00101-014-2404-x.
Diastolic heart failure leads to an increase in perioperative morbidity and mortality. The prevalence of this disease is rising and multiple risk factors have already been identified. Besides higher age and female gender, arterial hypertension, diabetes mellitus and coronary artery disease in particular have to be considered. Clinical examination and laboratory analyses are important for preoperative evaluation; however, echocardiography plays the most important role in the diagnostics of diastolic heart failure. The transmitral flow profile can be used to differentiate the grades of diastolic dysfunction using the ratio between early passive ventricular filling (E) and late active filling due to atrial contraction (A). Data concerning the ideal anesthesia technique are for the most part lacking; however, the application of thoracic epidural anesthesia seems to be beneficial. A great deal of attention has to be paid to the intraoperative volume status of patients with diastolic dysfunction as hypovolemia and hypervolemia can both have detrimental effects. Arrhythmias and major changes in blood pressure put this special group of patients at additional risks.
舒张性心力衰竭会导致围手术期发病率和死亡率增加。这种疾病的患病率正在上升,并且已经确定了多种危险因素。除了年龄较大和女性性别外,尤其必须考虑动脉高血压、糖尿病和冠状动脉疾病。临床检查和实验室分析对术前评估很重要;然而,超声心动图在舒张性心力衰竭的诊断中起着最重要的作用。二尖瓣血流频谱可用于通过早期被动心室充盈(E)与心房收缩导致的晚期主动充盈(A)之间的比率来区分舒张功能障碍的等级。关于理想麻醉技术的数据大多缺乏;然而,胸段硬膜外麻醉的应用似乎是有益的。对于舒张功能障碍患者的术中容量状态必须给予高度关注,因为低血容量和高血容量都可能产生有害影响。心律失常和血压的重大变化使这一特殊患者群体面临额外风险。