情感性和非情感性精神病中的社会功能与年龄
Social functioning and age across affective and nonaffective psychoses.
作者信息
Martin Elizabeth A, Öngür Dost, Cohen Bruce M, Lewandowski Kathryn E
机构信息
*Department of Psychology and Social Behavior, University of California, Irvine; †Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, MA; and ‡Department of Psychiatry, Harvard Medical School, Boston, MA.
出版信息
J Nerv Ment Dis. 2015 Jan;203(1):37-42. doi: 10.1097/NMD.0000000000000232.
Both nonaffective and affective psychoses are associated with deficits in social functioning across the course of the illness. However, it is not clear how social functioning varies among diagnostic groups as a function of age. The current study examined the relationship between social functioning and age in schizophrenia (SZ), schizoaffective disorder (SZA), and psychotic bipolar disorder (PBD). We found that individuals with PBD had the highest functioning, whereas individuals with SZ had the poorest. The functioning of individuals with SZA fell in between those of other groups. We also found that older ages were associated with poorer functioning. Although there was not a significant diagnostic group by age interaction, visual inspection of our data suggests a subtly steeper trajectory of decline in PBD. Overall, these results indicate that early interventions targeting social functioning may benefit individuals with either non-affective or affective psychoses to slow a projected decline.
非情感性和情感性精神病在疾病过程中均与社会功能缺陷相关。然而，目前尚不清楚社会功能在不同诊断组中如何随年龄变化。本研究考察了精神分裂症（SZ）、分裂情感性障碍（SZA）和伴有精神病性症状的双相情感障碍（PBD）患者的社会功能与年龄之间的关系。我们发现，PBD患者的功能水平最高，而SZ患者的功能最差。SZA患者的功能水平介于其他两组之间。我们还发现，年龄越大，功能越差。虽然年龄与诊断组之间没有显著的交互作用，但通过对数据的直观观察表明，PBD患者功能下降的轨迹略显陡峭。总体而言，这些结果表明，针对社会功能的早期干预可能有益于非情感性或情感性精神病患者，以减缓预期的功能衰退。
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