Department of Psychiatry, Ankara Mamak State Hospital, Ankara 06270, Turkey.
Department of Psychiatry, Ankara University School of Medicine, Ankara, Turkey.
Psychiatry Res. 2022 Nov;317:114845. doi: 10.1016/j.psychres.2022.114845. Epub 2022 Sep 13.
In our study we aimed to investigate the effect of the pandemic period on disease severity, medication adherence, suicidal behavior, physical health and health behavior in patients with psychotic disorders. 255 patients with any of the diagnoses of Schizophrenia, Schizoaffective Disorder, Delusional Disorder, Bipolar Disorder with psychotic features and Major Depressive Disorder with psychotic features were included, 200 were assessed by telephone and 55 face-to-face. The patient's sociodemographic status, cigarette-alcohol use, physical diseases, body weight, suicidal behaviors, and the effects of the pandemic period on general health were assessed. Clinical global impression scale(CGI) and modified medication adherence scale(MMS) were also administered. We showed that the MMS scores of the patients significantly decreased compared to the pre-pandemic period. In our study, suicidal behavior and decrease in medication adherence during the pandemic period were found to be correlated with higher scores of CGI- Severity and Improvement Scale. Our study is one of the few studies that addresses the effects of the pandemic period on patients with psychotic disorders. The results show that the pandemic period is associated with an increase in negative health behavior and clinical worsening in patients with psychotic disorders. In order to confirm these findings, more research is needed in this area.
在我们的研究中，我们旨在调查大流行期间对精神病患者疾病严重程度、药物依从性、自杀行为、身体健康和健康行为的影响。纳入了 255 名患有精神分裂症、分裂情感障碍、妄想障碍、有精神病特征的双相情感障碍和有精神病特征的重性抑郁障碍的患者，其中 200 名通过电话评估，55 名面对面评估。评估了患者的社会人口统计学状况、烟酒使用、身体疾病、体重、自杀行为以及大流行期间对一般健康的影响。还进行了临床总体印象量表（CGI）和改良药物依从性量表（MMS）的评估。我们发现，与大流行前相比，患者的 MMS 评分显著下降。在我们的研究中，大流行期间的自杀行为和药物依从性下降与 CGI-严重程度和改善量表的更高分数相关。我们的研究是少数研究大流行期间对精神病患者影响的研究之一。结果表明，大流行期间与精神病患者的负面健康行为和临床恶化有关。为了证实这些发现，需要在这一领域进行更多的研究。
