McCrossan B A, Walsh K P
Department of Paediatric Cardiology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.
Catheter Cardiovasc Interv. 2015 Apr;85(5):837-41. doi: 10.1002/ccd.25770. Epub 2014 Dec 27.
To evaluate Fontan fenestration closure using the Amplatzer Duct Occluder II device (ADO2).
Fontan fenestration closure is a well established catheter intervention. A range of occlusion devices developed for other interventions have been utilized. Most of these devices, and especially the most commonly used Amplatzer Septal Occluder, are relatively bulky. The ADO2 is a low profile, flexible, and inexpensive device which seems well suited to the Fontan fenestration.
This study details retrospective review of patients undergoing Fontan fenestration closure with an ADO2 device. Outcome measures included procedural success, pre- and post-procedural differences in oxygen saturation and mean pulmonary artery pressure and complications.
Thirteen patients were eligible for inclusion during the 34 month study period. All procedures were technically successful. There was a significant increase in oxygen saturations (Mean=+12%, P<0.01) after fenestration closure but no significant change in mean pulmonary artery pressure (Mean=+0.5 mm Hg, P=0.08). There were no procedural complications.
Fontan fenestration closure with the ADO2 device is a simple, short, and cost-effective procedure. The ADO2 characteristics recommend it to occlusion of varying sizes and morphologies of Fontan fenestration.
使用Amplatzer II型动脉导管封堵器（ADO2）评估Fontan开窗封堵术。
Fontan开窗封堵术是一种成熟的导管介入治疗方法。已采用了一系列为其他介入治疗开发的封堵装置。这些装置中的大多数，尤其是最常用的Amplatzer房间隔封堵器，相对体积较大。ADO2是一种外形小巧、柔韧性好且价格低廉的装置，似乎非常适合Fontan开窗封堵术。
本研究详细回顾了使用ADO2装置进行Fontan开窗封堵术的患者。观察指标包括手术成功率、术前和术后血氧饱和度及平均肺动脉压的差异以及并发症情况。
在34个月的研究期间，有13例患者符合纳入标准。所有手术在技术上均获成功。开窗封堵术后血氧饱和度显著升高（平均升高12%，P<0.01），但平均肺动脉压无显著变化（平均升高0.5 mmHg，P=0.08）。无手术相关并发症。
使用ADO2装置进行Fontan开窗封堵术是一种简单、耗时短且经济有效的手术。ADO2的特性使其适用于不同大小和形态的Fontan开窗封堵。
