Department of Obstetrics, Division of Fetal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Ultrasound Obstet Gynecol. 2015 Apr;45(4):439-46. doi: 10.1002/uog.14761. Epub 2015 Mar 5.
To determine, by expert consensus, the essential substeps of fetoscopic laser surgery (FLS) for twin-twin transfusion syndrome (TTTS) that could be used to create an authority-based curriculum for training in this procedure among fetal medicine specialists.
A Delphi survey was conducted among an international panel of experts (n = 98) in FLS. Experts rated the substeps of FLS on a five-point Likert-type scale to indicate whether they considered them to be essential, and were able to comment on each substep, using a dedicated online platform accessed by the invited tertiary care facilities that specialize in fetal therapy. Responses were returned to the panel until consensus was reached (Cronbach's α ≥ 0.80). All substeps that were rated ≥ 4 by 80% of the experts were included in the evaluation instrument.
After the first iteration of the Delphi procedure, a response rate of 74% (73/98) was reached, and in the second and third iterations response rates of 90% (66/73) and 81% (59/73) were reached, respectively. Among a total of 81 substeps rated in the first round, 21 substeps had to be re-rated in the second round. Finally, from the initial list of substeps, 55 were agreed by experts to be essential. In the third round, the 18 categorized substeps were ranked in order of importance, with 'coagulation of all anastomoses that cross the equator' and 'determination of fetoscope insertion site' as the most important.
A total of 55 substeps of FLS for TTTS were defined by a panel of experts to be essential in the procedure. This list is the first authority-based evidence to be used in the development of a final training model for future fetal surgeons.
通过专家共识确定胎儿镜激光手术(FLS)治疗双胎输血综合征(TTTS)的基本亚步骤,这些亚步骤可用于为胎儿医学专家制定该程序的基于权威的培训课程。
对 FLS 领域的国际专家小组(n=98)进行了 Delphi 调查。专家对 FLS 的亚步骤进行了五分制李克特量表评分,以表明他们是否认为这些亚步骤是必不可少的,并能够使用专门的在线平台对每个亚步骤进行评论,该平台由专门从事胎儿治疗的受邀三级医疗机构访问。答复被返回给小组,直到达成共识(Cronbach's α≥0.80)。所有被 80%的专家评为≥4 的亚步骤都包含在评估工具中。
在 Delphi 程序的第一轮之后,达到了 74%(73/98)的回复率,在第二轮和第三轮中,回复率分别为 90%(66/73)和 81%(59/73)。在第一轮中评估的总共 81 个亚步骤中,有 21 个亚步骤需要在第二轮中重新评估。最后,从最初的亚步骤列表中,专家一致认为有 55 个是必不可少的。在第三轮中,将 18 个分类的亚步骤按重要性排序,其中“所有跨越赤道的吻合口的止血”和“确定胎儿镜插入部位”是最重要的。
一组专家确定了 FLS 治疗 TTTS 的 55 个亚步骤是该程序的基本步骤。这份清单是第一个基于权威的证据,将用于未来胎儿外科医生的最终培训模型的开发。