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中国河南省支气管哮喘的流行病学及哮喘控制评估

Epidemiology of bronchial asthma and asthma control assessment in Henan Province, China.

作者信息

Zhang Wenping, Chen Xianliang, Ma Lijun, Wu Jizhen, Zhao Limin, Kuang Hongyan, Huang Taibo, Cheng Jianjian, Zhang Luoxian, Qi Yong, Sun Beibei, Niu Hongyan

机构信息

Department of Respiratory and Critical Care Medicine, People's Hospital of Henan Province, Zhengzhou University, Zhengzhou, Henan Province China.

出版信息

Transl Respir Med. 2014 Mar 5;2:5. doi: 10.1186/2213-0802-2-5. eCollection 2014.

Abstract

BACKGROUND

Prevalence of bronchial asthma, asthma treatment assessment, and estimation of the control level among asthma patients in Henan Province, China are reported in this paper.

METHODS

We selected 10 among the 109 cities and districts in Henan province using a multistage stratified cluster random sampling method. A total of 500 households from each city and district were chosen. Approximately 20,000 residents from a total of 5,000 households were randomly selected to answer a questionnaire recommended by the China Asthma Alliance. Asthma patients were asked to answer a detailed questionnaire using the symptom-based guidelines to assess the levels of disease control.

RESULTS

The overall prevalence of asthma was 0.73% ± 0.12%. Urban and rural residents had asthma prevalence rates of 1.1% ± 0.23% (88/7,924) and 0.48% ± 0.12% (57/11,792), respectively. Among the asthma patients, only 33.8% (52) received regular medication, 25% (13) used oral glucocorticoids, and 71.1% (37) used oral theophylline. The classified control levels of patients were as follows: 33.1% controlled, 49.7% partially controlled, and 17.2% uncontrolled. A total of 38.5% and 27.5% of regularly and irregularly treated asthma patients reached controlled level, respectively. The two groups significantly differed in asthma control level.

CONCLUSION

Asthma prevalence is low in Henan Province, China. Urban residents have higher prevalence of asthma than rural residents do. Patients with asthma receive insufficient medication, resulting in suboptimal asthma control. Improvement in diagnosis and treatment of asthma patients is urgently needed.

摘要

背景

本文报告了中国河南省支气管哮喘的患病率、哮喘治疗评估以及哮喘患者控制水平的估计情况。

方法

我们采用多阶段分层整群随机抽样方法,从河南省109个市辖区中选取了10个。每个市辖区共选取500户家庭。从总共5000户家庭中随机抽取约20000名居民,回答中国哮喘联盟推荐的问卷。哮喘患者被要求使用基于症状的指南回答一份详细问卷,以评估疾病控制水平。

结果

哮喘的总体患病率为0.73%±0.12%。城乡居民的哮喘患病率分别为1.1%±0.23%(88/7924)和0.48%±0.12%(57/11792)。在哮喘患者中,只有33.8%(52人)接受常规药物治疗,25%(13人)使用口服糖皮质激素,71.1%(37人)使用口服茶碱。患者的分类控制水平如下:33.1%控制良好,49.7%部分控制,17.2%未控制。接受常规和非常规治疗的哮喘患者分别有38.5%和27.5%达到控制水平。两组在哮喘控制水平上有显著差异。

结论

中国河南省哮喘患病率较低。城市居民的哮喘患病率高于农村居民。哮喘患者用药不足,导致哮喘控制不理想。迫切需要改善哮喘患者的诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77cb/4215820/98ed0597292b/40247_2013_18_Fig1_HTML.jpg

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