沙特阿拉伯卡西姆地区一家医院的癫痫概况
Profile of epilepsy in a regional hospital in Al qassim, saudi arabia.
作者信息
Hamdy Nermin A, Alamgir Mohammad Jawad, Mohammad El Gamri E, Khedr Mahmoud H, Fazili Shafat
机构信息
Minia University, Egypt.
College of Medicine, Al Qassim University, Al Qassim, Saudi Arabia.
出版信息
Int J Health Sci (Qassim). 2014 Jul;8(3):247-55. doi: 10.12816/0023977.
INTRODUCTION
Epilepsy is a diverse set of chronic neurological disorders characterized by seizures. It is one of the most common of the serious neurological disorders. About 3% of people will be diagnosed with epilepsy at some time in their lives.
OBJECTIVES
We aimed to address the commonest types of seizures, their aetiologies, EEG and neuroimaging results and prognosis of patients presented to neurology services of the King Fahad Specialist Hospital- AlQassim (KFSH).
METHODOLOGY
In this retrospective epidemiological study we investigated the medical records of patients with epilepsy, who attended the neurology services of KFSH, during the study period (26/10/2011-26/4/2012).
RESULTS
The study included 341 patients; 189 (55.4%) males and 152 (44.6%) females. Their ages ranged between 12 and 85 years (mean ± SD = 31±16.9). The majority of patients had Generalised Tonic Clonic Seizures (76.2%), followed by Complex Partial Seizures (7.6%). 73% of our patients had idiopathic epilepsy. The commonest causes for symptomatic epilepsy were Cerebro Vascular Accidents and Head trauma. Hemiplegia, mental retardation and psychiatric illness were the commonest comorbidity. 69.3% of patients had controlled seizures. Patients with idiopathic epilepsy were significantly controlled than patients with symptomatic epilepsy (P=0.01), and those using one Anti Epileptic Drug were significantly controlled compared to patients using polytherapy (P=0.0001) there was no significant relation between controlled seizure and duration of illness or hospitalization or EEG changes.
CONCLUSION
Seizure types, aetiology, drug therapy, Comorbidities and outcome in a tertiary care hospital in Saudi Arabia are similar to previous local and international studies. 35.3% of patients were hospitalized, higher rates than previous studies. Seizure control was better in generalized seizures and idiopathic epilepsy compared to complex partial seizures or partial seizures with secondary generalization and symptomatic epilepsy.
引言
癫痫是一组以发作性症状为特征的慢性神经系统疾病。它是最常见的严重神经系统疾病之一。约3%的人在其一生中的某个时候会被诊断为癫痫。
目的
我们旨在探讨法赫德国王专科医院 - 卡西姆分院（KFSH）神经科门诊患者中最常见的癫痫发作类型、病因、脑电图和神经影像学结果以及预后情况。
方法
在这项回顾性流行病学研究中，我们调查了研究期间（2011年10月26日 - 2012年4月26日）在KFSH神经科就诊的癫痫患者的病历。
结果
该研究纳入了341例患者；男性189例（55.4%），女性152例（44.6%）。他们的年龄在12岁至85岁之间（平均±标准差 = 31±16.9）。大多数患者患有全身强直阵挛性发作（76.2%），其次是复杂部分性发作（7.6%）。73%的患者患有特发性癫痫。症状性癫痫最常见的病因是脑血管意外和头部外伤。偏瘫、智力低下和精神疾病是最常见的合并症。69.3%的患者癫痫发作得到控制。特发性癫痫患者的发作控制情况明显优于症状性癫痫患者（P = 0.01），并且使用一种抗癫痫药物的患者与使用多种药物治疗的患者相比，发作控制情况明显更好（P = 0.0001）。癫痫发作控制与病程、住院时间或脑电图变化之间没有显著关系。
结论
沙特阿拉伯一家三级医疗医院的癫痫发作类型、病因、药物治疗、合并症及预后与先前的本地和国际研究相似。35.3%的患者住院治疗，这一比例高于先前的研究。与复杂部分性发作或继发全身性发作的部分性发作及症状性癫痫相比，全身性发作和特发性癫痫的发作控制情况更好。
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