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沙特阿拉伯王国一家三级护理医院的癫痫流行病学研究。

Epidemiological study of epilepsy from a tertiary care hospital in kingdom of Saudi Arabia.

作者信息

Shahid Rizwana, Nazish Saima, Zafar Azra, Aljafaari Danah, Alabdali Majed, Ishaque Noman, Alzahrani Bayan A, Alkhamis Fahad A

机构信息

Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Alkhobar, Kingdom of Saudi Arabia. E-mail:

出版信息

Neurosciences (Riyadh). 2018 Jul;23(3):223-226. doi: 10.17712/nsj.2018.3.20180062.

DOI:10.17712/nsj.2018.3.20180062
PMID:30007998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8015582/
Abstract

OBJECTIVE

To identify the types of seizures and describe the clinical features, EEG and radiological findings among patients with epilepsy.

METHODS

In this retrospective epidemiological study, we analyzed the medical records of the patients with the diagnosis of epilepsy during the study period (January 1st 2016- December 2016) RESULTS: The study included 184 patients, 91 (49.5%) were males and 93 (50.5%) females. Age ranged between 12 and 85 years (mean 35.4+/-19.5 SD years). Most of the patients 150 (82%) had Generalized tonic clonic seizures followed by focal onset in 27 (14%) of the patients. Main EEG abnormality was focal to bilateral was recorded in 53 (41%), idiopathic/ cryptogenic epilepsy was diagnosed in 61% of the patients. The most common abnormalities on brain imaging were temporal/hippocampal atrophy/stroke. The most common cause of symptomatic epilepsy was stroke found in 20(11%) followed by post infectious epilepsy and head trauma.

CONCLUSION

Seizure types, EEG characteristics and etiologies of symptomatic epilepsy in our cohort of patients are in accordance with the current literature. Slight discrepancy observed in gender distribution and etiologies for symptomatic epilepsy compared with other studies from Saudi Arabia need to be studied further by prospective and population base studies.

摘要

目的

确定癫痫发作类型,并描述癫痫患者的临床特征、脑电图和影像学检查结果。

方法

在这项回顾性流行病学研究中,我们分析了研究期间(2016年1月1日至2016年12月)诊断为癫痫的患者的病历。结果:该研究纳入了184例患者,其中男性91例(49.5%),女性93例(50.5%)。年龄在12岁至85岁之间(平均35.4±19.5标准差岁)。大多数患者150例(82%)有全身强直阵挛发作,其次是27例(14%)患者出现局灶性发作。脑电图主要异常表现为从局灶性到双侧性的有53例(41%),61%的患者被诊断为特发性/隐源性癫痫。脑成像最常见的异常是颞叶/海马萎缩/中风。症状性癫痫最常见的病因是中风,有20例(11%),其次是感染后癫痫和头部外伤。

结论

我们队列中癫痫患者的发作类型、脑电图特征和症状性癫痫的病因与当前文献一致。与沙特阿拉伯其他研究相比,在性别分布和症状性癫痫病因方面观察到的细微差异需要通过前瞻性和基于人群的研究进一步探讨。

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本文引用的文献

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Profile of epilepsy in a regional hospital in Al qassim, saudi arabia.沙特阿拉伯卡西姆地区一家医院的癫痫概况
Int J Health Sci (Qassim). 2014 Jul;8(3):247-55. doi: 10.12816/0023977.
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