Pozzi Matteo, Grinberg Daniel, Obadia Jean-François, Saroul Christine, Green Lisa, Dementhon Julie, Pizzighini Sarah, Rioufol Gilles, Finet Gerard, Modine Thomas
Department of Cardiac Surgery, "Louis Pradel" Cardiologic Hospital, Hospices Civils de Lyon, "Claude Bernard" University, Lyon, France.
Department of Anesthesia-Reanimation, "Louis Pradel" Cardiologic Hospital, Hospices Civils de Lyon, "Claude Bernard" University, Lyon, France.
Catheter Cardiovasc Interv. 2015 Jun;85(7):E203-9. doi: 10.1002/ccd.25779. Epub 2014 Dec 27.
To assess the feasibility and safety of transcatheter aortic valve implantation (TAVI) through a left transcarotid approach in patients previously operated on for ipsilateral carotid endarterectomy (CEA).
The healthcare impact of extracranial carotid artery disease is essential as stroke is the third-leading cause of death in industrialized nations and CEA is often present in the history of patients awaiting TAVI.
The primary endpoint was to evaluate 30-day mortality and freedom from major TAVI-related complications in an observational analysis.
From December 2011 to February 2014, we performed 9 TAVI. The mean age was 84.6 years. The procedure was performed without any technical complication or vascular injury in every patient. There was neither intraoperative mortality nor intraoperative major complications. One (11.1%) patient experienced spatial-temporal disorientation but cerebral computed tomography did not show any sign of stroke. Two (22.2%) patients needed the implantation of a pacemaker due to third-degree atrioventricular block appearance. Three (33.3%) patients were transfused with packed red blood cells and 1 (11.1%) patient developed a groin hematoma. Only 1 (11.1%) patient showed a residual paravalvular regurgitation ≥ 2. At 30-day follow-up there was neither mortality nor other TAVI-related complications and echocardiography parameters remained stable.
TAVI through a left transcarotid approach in patients previously operated on for ipsilateral CEA is feasible and safe. The presence of a previous ipsilateral CEA represents no more a limitation to the utilization of this promising access route. At short-term follow-up, mortality and major complications rates are low.
评估经左颈动脉途径行导管主动脉瓣植入术(TAVI)在既往同侧颈动脉内膜切除术(CEA)患者中的可行性和安全性。
颅外颈动脉疾病对医疗保健的影响至关重要,因为中风是工业化国家第三大死因,且等待TAVI的患者病史中常出现CEA。
在一项观察性分析中,主要终点是评估30天死亡率和无重大TAVI相关并发症情况。
2011年12月至2014年2月,我们进行了9例TAVI。平均年龄为84.6岁。每位患者手术均无任何技术并发症或血管损伤。既无术中死亡也无术中重大并发症。1例(11.1%)患者出现时空定向障碍,但脑部计算机断层扫描未显示任何中风迹象。2例(22.2%)患者因出现三度房室传导阻滞需要植入起搏器。3例(33.3%)患者输注了浓缩红细胞,1例(11.1%)患者出现腹股沟血肿。仅1例(11.1%)患者出现≥2级的瓣周残余反流。在30天随访时,既无死亡也无其他TAVI相关并发症,且超声心动图参数保持稳定。
在既往行同侧CEA手术的患者中经左颈动脉途径行TAVI是可行且安全的。既往同侧CEA的存在不再是使用这种有前景的入路的限制因素。在短期随访中,死亡率和重大并发症发生率较低。