Zhao Zheng, Wang Yanyan, Jin Jingyu, Deng Xiaohu, Huang Feng
Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China.
Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853, China. Email:
Zhonghua Nei Ke Za Zhi. 2014 Sep;53(9):724-9.
To study the imaging features of sacroiliac joints (SIJ) in patients who were misdiagnosed as spondyloarthritis (SpA).
A total of 34 patients with chief complaint of back pain and misdiagnosed as SpA from January 2007 to April 2013 in Department of Rheumatology Chinese PLA General Hospital were enrolled. The imaging, clinical manifestations, laboratory examinations data were analyzed.
The main reason for misdiagnosis as SpA was because of sacroiliitis presenting on imaging. The final diagnoses included 24 patients as SIJ infection, 4 patients as neoplastic diseases, 2 patients as metabolic bone diseases, 2 patients as sacroiliac joint degeneration, 1 patient as gout of sacroiliac joint, 1 patient as diffuse idiopathic bone hypertrophy. For patients with infection, there were 10 patients receiving X-ray and 22 patients receiving CT of SIJ. However, 5 and 7 patients had negative results respectively. These patients with infection had abnormalities in MRI including all with bone marrow edema, 21 patients with erosion of bone and joint, 22 patients with muscle involved. As to the patients with malignancies, SIJ CT scan appeared normal. Bone marrow edema and erosion in MRI were found in all neoplasm patients expect one as ependymoma. Adjacent muscles were involved in the patient with Ewing's sarcoma. Either X-ray or CT in other patients demonstrated obvious abnormalities, but only mild erosion of bone was found in MRI.
Bone marrow edema of SIJ in MRI represented not only in patients with SpA. Rheumatologists should analyze the clinical manifestations and laboratory examinations comprehensively in order to avoid the misdiagnoses.
研究被误诊为脊柱关节炎(SpA)的患者骶髂关节(SIJ)的影像学特征。
纳入2007年1月至2013年4月在中国人民解放军总医院风湿科以背痛为主诉且被误诊为SpA的34例患者。对其影像学、临床表现、实验室检查数据进行分析。
误诊为SpA的主要原因是影像学上出现骶髂关节炎。最终诊断包括24例为SIJ感染,4例为肿瘤性疾病,2例为代谢性骨病,2例为骶髂关节退变,1例为骶髂关节痛风,1例为弥漫性特发性骨肥厚。对于感染患者,10例接受了SIJ的X线检查,22例接受了CT检查。然而,分别有5例和7例结果为阴性。这些感染患者的MRI有异常,包括均有骨髓水肿,21例有骨与关节侵蚀,22例有肌肉受累。对于恶性肿瘤患者,SIJ的CT扫描表现正常。除1例室管膜瘤外,所有肿瘤患者的MRI均发现骨髓水肿和侵蚀。尤因肉瘤患者的邻近肌肉受累。其他患者的X线或CT均显示明显异常,但MRI仅发现轻度骨侵蚀。
MRI显示的SIJ骨髓水肿不仅见于SpA患者。风湿科医生应综合分析临床表现和实验室检查以避免误诊。