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心脏导管插入术后立即进行血液透析是透析期间低血压的一个危险因素。

Hemodialysis immediately after cardiac catheterization is a risk factor for intradialytic hypotension.

作者信息

Irifuku Taisuke, Naito Takayuki, Ogawa Takahiko, Shimizu Yuka, Maeoka Yujiro, Masaki Takao

机构信息

Department of Nephrology, Hiroshima University Hospital, Hiroshima, Japan.

Centre for Kidney Diseases, Hiroshima Prefectural Hospital, Hiroshima, Japan.

出版信息

Ther Apher Dial. 2015 Jun;19(3):245-9. doi: 10.1111/1744-9987.12252. Epub 2014 Dec 16.

Abstract

Many hemodialysis clinicians have noticed that patients frequently develop intradialytic hypotension (IDH) immediately after cardiac catheterization (CC). However, precise data about the incidence of IDH immediately after CC are scarce. This study involved a single-center, retrospective, cross-sectional design. We reviewed the medical records of all HD patients who underwent CC between January 2009 and March 2012 at Hiroshima Prefectural Hospital. IDH was defined as a fall of systolic blood pressure of more than 20 mm Hg or a fall of mean blood pressure of more than 10 mm Hg, with symptoms according to the K/DOQI criteria. Data on a total of 112 patients were obtained: 64 patients commenced HD immediately after CC (IA group) and 48 patients underwent HD on the day after CC (ND group). The overall incidence of IDH was 34% (38/112). The incidence of IDH was significantly higher in the IA group than in the ND group (27/64, 42% vs. 11/48, 23%; P < 0.05). Multivariate logistic regression analysis showed that IA (odds ratio, 5.39; 95% confidence interval, 1.76 to 16.49; P < 0.01), coronary stenosis (odds ratio, 4.16; 95% confidence interval, 1.49 to 11.64; P < 0.05) were independently associated with IDH. This study revealed that HD immediately after CC is associated with a higher incidence of IDH. Clinicians should consider that HD following CC be scheduled for the next day, especially in patients with coronary stenosis.

摘要

许多血液透析临床医生注意到,患者在心脏导管插入术(CC)后常常立即出现透析中低血压(IDH)。然而,关于CC后立即发生IDH的发生率的精确数据却很稀少。本研究采用单中心、回顾性、横断面设计。我们回顾了2009年1月至2012年3月期间在广岛县立医院接受CC的所有血液透析患者的病历。IDH的定义为收缩压下降超过20 mmHg或平均血压下降超过10 mmHg,并伴有符合K/DOQI标准的症状。共获得112例患者的数据:64例患者在CC后立即开始血液透析(IA组),48例患者在CC后第二天进行血液透析(ND组)。IDH的总体发生率为34%(38/112)。IA组IDH的发生率显著高于ND组(27/64,42%对11/48,23%;P<0.05)。多因素逻辑回归分析显示,IA(比值比,5.39;95%置信区间,1.76至16.49;P<0.01)、冠状动脉狭窄(比值比,4.16;95%置信区间,1.49至11.64;P<0.05)与IDH独立相关。本研究表明,CC后立即进行血液透析与IDH的较高发生率相关。临床医生应考虑将CC后的血液透析安排在第二天,尤其是对于有冠状动脉狭窄的患者。

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