Emerg Med J. 2015 Jan;32(1):85-8. doi: 10.1136/emermed-2014-204467.1.
A shortcut review was carried out to establish whether intravenous glucagon is a safe and effective treatment for patients with suspected lower oesophageal food bolus impaction. Seven studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that there is no evidence for the effectiveness of glucagon in this situation. Its use may be associated with adverse effects such as vomiting, with the potential risk of oesophageal perforation. Intravenous glucagon should therefore be avoided.
进行了一项简短综述,以确定静脉注射胰高血糖素对疑似食管下段食物团块嵌塞患者是否为一种安全有效的治疗方法。七项研究与该问题直接相关。这些论文的作者、发表日期和国家、所研究的患者组、研究类型、相关结局、结果及研究不足均列于表格中。临床结论是,没有证据表明胰高血糖素在这种情况下有效。其使用可能会伴有呕吐等不良反应,存在食管穿孔的潜在风险。因此,应避免使用静脉注射胰高血糖素。