宿主对焦化上皮增生中乳头瘤病毒的反应。
Host response to papilloma virus in focal epithelial hyperplasia.
作者信息
Hernández-Jáuregui P, Tamayo Pérez R, Pazbueso H R
出版信息
Ann Dent. 1989 Summer;48(1):8-12, 52.
PMID:2551213
Abstract
The ultrastructural features of the lesions of four FEH patients disclosed changes in the nuclei interpreted as a premature disintegration of the nucleoli and the presence of papilloma-like viruses. Changes in ribosome number and distribution, glycogen content and formation of vesicles within the cytoplasm of FEH keratinocytes were observed and compared with normal epithelia. The observed cell changes were explained as specific host response due to HPV-13.
摘要
4例局灶性上皮增生（FEH）患者病变的超微结构特征显示，细胞核变化表现为核仁过早解体，且存在乳头瘤样病毒。观察了FEH角质形成细胞胞质内核糖体数量和分布、糖原含量及囊泡形成的变化，并与正常上皮进行比较。观察到的细胞变化被解释为是由人乳头瘤病毒13型（HPV - 13）引起的特异性宿主反应。
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