Matsui Y, Kanoh H, Okudaira Y, Hashimoto T, Nakamura H
Dept. of Gynecology, Osaka University.
Gan To Kagaku Ryoho. 1989 Aug;16(8 Pt 2):2801-4.
Transcatheter-arterial-chemo-embolization (TACE) was performed on 7 cases of uterine cervical cancer from T1b to T3b. The purpose of this approach is to stop the uterine bleeding caused by malignancy and disrupt the cancer cells under the feeding arteries. TACE by Seldinger's method was undertaken selectively on both uterine arteries with suspension of Lipiodol, Adriamycin and Gelfoam. In each case, the bleeding stopped soon after the operation, and the lesion began to necrose within a few days. Though the primary effects were confirmed, complete remission could not be expected, so radiation therapy was performed. The longest survival among these patients was over 6 years. It should be noted that the other major advantage claimed for TACE is to decrease the dose of radiation.
对7例T1b至T3b期宫颈癌患者实施了经动脉化疗栓塞术(TACE)。该方法的目的是阻止恶性肿瘤引起的子宫出血,并破坏供血动脉下的癌细胞。采用Seldinger法对双侧子宫动脉进行选择性TACE,注入碘油、阿霉素和明胶海绵。每例患者术后出血很快停止,病变在数天内开始坏死。虽然初步效果得到证实,但无法预期完全缓解,因此进行了放射治疗。这些患者中最长生存期超过6年。应当指出,TACE的另一个主要优点是可减少放疗剂量。