Uz Ali Osman, Kenar Fethullah, Yıldız Hüseyin, Duran Abidin, Tekin Mustafa Said, Ayçiçek Abdullah
Department of Otolaryngology, Acıpayam State Hospital, Denizli, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2014 Sep-Oct;24(5):247-53. doi: 10.5606/kbbihtisas.2014.25986.
This study aims to investigate the effect of radiofrequency thermal ablation (RFTA) treatment on nasal mucociliary activity before and after treatment in inferior turbinate hypertrophy.
Thirty-nine patients (21 males, 18 females; mean age 36.3±13.9 years; range 16 to 67 years) admitted to our clinic with complaint of nasal obstruction and diagnosed with stromal inferior turbinate hypertrophy were included in this study. Effect of RFTA treatment on nasal mucociliary activity was investigated by saccharine test before treatment and two months after treatment. Grade of nasal obstruction was evaluated by visual analog scale (VAS) before treatment and two months after treatment. Results were compared with paired t-test.
Mean mucociliary activity times were 9.8±4.4 minutes before treatment and 9.6±4.1 minutes two months after treatment, and the difference between two tests was not statistically significant (p=0.3). Mean VAS scores for nasal obstruction were 6.5±1.2 before treatment and 3.8±1.0 two months after treatment, and the difference between two results was statistically significant (p=0.001). Difference between sexes in terms of saccharine transit time and VAS values before and after treatment was not statistically significant (p>0.05).
It was detected that RFTA has no adverse effect on mucociliary activity in the treatment of inferior turbinate hypertrophy, and this method is notably effective in relieving the nasal obstruction caused by inferior turbinate hypertrophy.
本研究旨在探讨射频热消融（RFTA）治疗对下鼻甲肥大患者治疗前后鼻黏膜纤毛活动的影响。
本研究纳入了39例因鼻塞症状入院且被诊断为基质性下鼻甲肥大的患者（21例男性，18例女性；平均年龄36.3±13.9岁；年龄范围16至67岁）。通过糖精试验在治疗前及治疗后两个月研究RFTA治疗对鼻黏膜纤毛活动的影响。采用视觉模拟量表（VAS）在治疗前及治疗后两个月评估鼻塞程度。结果采用配对t检验进行比较。
治疗前平均纤毛活动时间为9.8±4.4分钟，治疗后两个月为9.6±4.1分钟，两次测试结果的差异无统计学意义（p = 0.3）。治疗前鼻塞的平均VAS评分为6.5±1.2，治疗后两个月为3.8±1.0，两次结果的差异有统计学意义（p = 0.001）。治疗前后糖精转运时间和VAS值在性别方面的差异无统计学意义（p>0.05）。
研究发现RFTA治疗下鼻甲肥大对纤毛活动无不良影响，且该方法在缓解下鼻甲肥大引起的鼻塞方面效果显著。
