Öztürk Murat, Ila Kadri, Düzgöl Cihan, Akansel Gür, Almaç Ahmet
Department of Otolaryngology, Medical Faculty of Kocaeli University, 41380 Umuttepe, Kocaeli, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2014 Sep-Oct;24(5):287-91. doi: 10.5606/kbbihtisas.2014.37029.
Leptomeningeal carcinomatosis is a rare condition characterized by diffuse infiltration of the meninges after the metastasis of the solid tumors. Bilateral sudden hearing loss is a rare initial symptom. In this article, we report a 44-year-old male patient with bilateral sudden hearing loss and dizziness. Magnetic resonance imaging showed involvement of the bilateral vestibulocochlear nerves. Malignant cells were detected in cerebrospinal fluid cytology. To the best of our knowledge, leptomeningeal carcinomatosis due to duodenum adenocarcinoma has not been reported before in the English literature. Leptomeningeal carcinomatosis should be kept in mind in patients who have bilateral sudden sensorineural hearing loss.
柔脑膜癌病是一种罕见疾病，其特征为实体瘤转移后脑膜的弥漫性浸润。双侧突发听力丧失是一种罕见的首发症状。在本文中，我们报告了一名44岁男性患者，其出现双侧突发听力丧失和头晕。磁共振成像显示双侧前庭蜗神经受累。脑脊液细胞学检查发现了恶性细胞。据我们所知，十二指肠腺癌所致的柔脑膜癌病在英文文献中此前未见报道。对于出现双侧突发感音神经性听力丧失的患者，应考虑柔脑膜癌病。
