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在解开早期发声的影响和神经生物学基础的过程中:从雷特综合征中学习。

En route to disentangle the impact and neurobiological substrates of early vocalizations: learning from Rett syndrome.

机构信息

Institute of Physiology,Research Unit iDN - Interdisciplinary Developmental Neuroscience,Medical University of Graz Austria,8010 Graz,

Department of Neurology,Boston Children's Hospital and Harvard Medical School,Boston,MA

出版信息

Behav Brain Sci. 2014 Dec;37(6):562-3; discussion 577-604. doi: 10.1017/S0140525X1300410X.

Abstract

Research on acoustic communication and its underlying neurobiological substrates has led to new insights about the functioning of central pattern generators (CPGs). CPG-related atypicalities may point to brainstem irregularities rather than cortical malfunctions for early vocalizations/babbling. The "vocal pattern generator," together with other CPGs, seems to have great potential in disentangling neurodevelopmental disorders and potentially predict neurological development.

摘要

对声通讯及其潜在神经生物学基础的研究,为中枢模式发生器(CPG)的功能提供了新的见解。CPG 相关的非典型性可能指向脑干异常,而不是早期发声/咿呀学语的皮质功能障碍。“发声模式发生器”与其他 CPG 一起,似乎在解开神经发育障碍方面具有巨大潜力,并可能预测神经发育。

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