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肺动脉腔内束带术的可行性及相关结果

Feasibility and related outcome of intraluminal pulmonary artery banding.

作者信息

Sandrio Stany, Purbojo Ariawan, Arndt Florian, Toka Okan, Glöckler Martin, Dittrich Sven, Cesnjevar Robert, Rüffer André

机构信息

Department of Pediatric Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

Department of Pediatric Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

出版信息

Eur J Cardiothorac Surg. 2015 Sep;48(3):470-80. doi: 10.1093/ejcts/ezu464. Epub 2014 Dec 16.

Abstract

OBJECTIVES

This retrospective study evaluated the feasibility and related outcome of intraluminal pulmonary artery banding (I-PAB).

METHODS

Thirty-two children underwent I-PAB between July 2006 and April 2014. The median age and weight were 60 days (range: 5 days to 4.2 years) and 3.7 kg (range: 2.6-13.0 kg), respectively. Cardiac diagnoses included single ventricle morphology (n = 11), complex ventricular septal defects (n = 11), balanced atrioventricular septal defects (n = 3), congenitally corrected transposition of the great arteries (n = 2) and aortic arch hypoplasia with ventricular septal defects (n = 5). On cardiopulmonary bypass (CPB), 2 I-PAB modifications with either 1 (n = 24) or 2 ('hour-glass-technique', n = 8) fenestrated pericardial patches were performed.

RESULTS

The median fenestration size was 5 mm (range: 4-6.5 mm). In 18 patients I-PAB was a solitary procedure; in 3 of them the decision was made intraoperatively. There was no hospital mortality. The median interval to debanding was 189 days (range: 112 days to 2.6 years). During this period, we observed a significant increase in the pressure gradient over I-PAB (P < 0.01), whereas arterial saturations remained stable. Four patients received balloon dilatation of I-PAB to prolong the palliation period. No patient experienced band occlusion, pulmonary hypertension related to I-PAB, coronary or pulmonary valve impairment. Debanding was performed in 27 patients and one of them required pulmonary patch arterioplasty due to I-PAB-associated pulmonary trunk distortion. Three patients are still awaiting further surgery. There were 2 late deaths prior to, and 3 after debanding, all not related to I-PAB.

CONCLUSIONS

I-PAB with an exactly defined internal orifice is feasible and effective. Although arterial saturations seem to remain stable, balloon dilatation of I-PAB can be performed safely and efficiently in order to prolong the palliation period. The rate of I-PAB-related complications is low, which might improve the long-term patient outcome. Therefore, despite requiring CPB, I-PAB is our institutional preference for children who require pulmonary artery banding.

摘要

目的

本回顾性研究评估了腔内肺动脉环扎术(I-PAB)的可行性及相关结果。

方法

2006年7月至2014年4月期间,32例儿童接受了I-PAB手术。年龄中位数和体重中位数分别为60天(范围:5天至4.2岁)和3.7千克(范围:2.6 - 13.0千克)。心脏诊断包括单心室形态(n = 11)、复杂室间隔缺损(n = 11)、平衡型房室间隔缺损(n = 3)、先天性矫正型大动脉转位(n = 2)以及合并室间隔缺损的主动脉弓发育不全(n = 5)。在体外循环(CPB)期间,采用两种I-PAB改良方法,分别使用1个(n = 24)或2个(“沙漏技术”,n = 8)带孔心包补片。

结果

带孔大小中位数为5毫米(范围:4 - 6.5毫米)。18例患者I-PAB为单独手术,其中3例在术中做出该决定。无住院死亡病例。去环扎的中位间隔时间为189天(范围:112天至2.6年)。在此期间,我们观察到I-PAB上的压力梯度显著增加(P < 0.01),而动脉血氧饱和度保持稳定。4例患者接受了I-PAB球囊扩张以延长姑息治疗期。无患者出现环扎闭塞、与I-PAB相关的肺动脉高压、冠状动脉或肺动脉瓣损伤。27例患者进行了去环扎手术,其中1例因I-PAB相关的肺动脉干扭曲需要进行肺动脉补片血管成形术。3例患者仍在等待进一步手术。去环扎术前有2例晚期死亡,去环扎术后有3例晚期死亡,均与I-PAB无关。

结论

具有精确界定内口的I-PAB是可行且有效的。尽管动脉血氧饱和度似乎保持稳定,但I-PAB球囊扩张可安全有效地进行,以延长姑息治疗期。I-PAB相关并发症发生率低,这可能改善患者的长期预后。因此,尽管需要CPB,但对于需要肺动脉环扎的儿童,I-PAB是我们机构的首选方法。

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