Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Genea Biocells Pty Limited, Sydney, NSW 2000, Australia.
Gaibian Associates, 257 River Valley Road, Singapore 138638.
Cell Stem Cell. 2014 Nov 6;15(5):531-2. doi: 10.1016/j.stem.2014.10.011.
Somatic cell nuclear transfer offers an alternative approach to the use of exogenous transcription factors for the reprogramming of somatic cells. But is it a better way? Two groups have performed detailed molecular comparisons between human cell lines made by the two methods and report different conclusions.
体细胞核移植为体细胞的重编程提供了一种替代方法，即使用外源转录因子。但是，这是一种更好的方法吗？两个研究小组对这两种方法制备的人细胞系进行了详细的分子比较，并得出了不同的结论。
