Rev Med Suisse. 2014 Oct 22;10(447):1961-2, 1964-6, 1968.
As a result of advances in oncologic treatment, a growing number of women diagnosed with cancer may envisage cure. Young women diagnosed with cancer often have a desire to fall pregnant in the future or may even be diagnosed with cancer in the process of family planning. The potential gonadotoxic effect of certain chemotherapeutic agents is well described. Therefore, it is essential that all women concerned about their fertility receive counselling from a reproductive medicine specialist to discuss the fertility preservation options. Currently, ovarian stimulation with cryopreservation of oocytes or fertilized oocytes is the treatment of choice. However, other options such as in vitro maturation or ovarian tissue cryopreservation should be discussed if ovarian stimulation is contraindicated.
由于肿瘤治疗的进展,越来越多被诊断患有癌症的女性可能期望治愈。被诊断患有癌症的年轻女性通常希望未来怀孕,甚至可能在计划生育过程中被诊断出患有癌症。某些化疗药物潜在的性腺毒性作用已有充分描述。因此,所有担心自己生育能力的女性都必须接受生殖医学专家的咨询,以讨论生育力保存的选择。目前,卵母细胞或受精卵冷冻保存的卵巢刺激是首选治疗方法。然而,如果卵巢刺激存在禁忌证,则应讨论其他选择,如体外成熟或卵巢组织冷冻保存。