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二价盐溶液中牛血清白蛋白的圆二色性

Circular dichroism of bovine serum albumin in divalent salt solutions.

作者信息

Sun S F, Maximos A S

机构信息

Department of Chemistry, St. John's University, Jamaica, New York.

出版信息

Int J Pept Protein Res. 1989 Jul;34(1):46-51. doi: 10.1111/j.1399-3011.1989.tb01007.x.

Abstract

The circular dichroism of bovine serum albumin in divalent salt solutions was investigated. The salts selected were magnesium chloride and calcium chloride. Their effects on the secondary and tertiary structures of the protein were compared with that of lithium chloride. It is well known that the elements Ca, Mg, and Li have many properties in common. The results show the similarity of their ions in the capacity of deforming protein, in spite of their characteristic pharmacological functions.

摘要

研究了牛血清白蛋白在二价盐溶液中的圆二色性。所选的盐为氯化镁和氯化钙。将它们对蛋白质二级和三级结构的影响与氯化锂的影响进行了比较。众所周知,钙、镁和锂元素有许多共同特性。结果表明,尽管它们具有独特的药理功能,但其离子在使蛋白质变形的能力方面具有相似性。

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