Sohail Shagufta, Afzal Muhammad, Anwar Vaqas, Shama Quratulain
Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S259-61.
Bacille Calmette-Guerin (BCG) vaccine is administered to all newborns in countries where tuberculosis is still endemic. It is a live attenuated vaccine and considered quite safe in immunocompetent children. Disseminated BCG disease is the most serious complication seen only in individuals with underlying primary or secondary immunodeficiencies. We report a case of disseminated BCG disease in an infant with Severe Combined Immunodeficiency (SCID) who received BCG administration prior to diagnosis of SCID.
在结核病仍然流行的国家，所有新生儿都接种卡介苗（BCG）疫苗。它是一种减毒活疫苗，在免疫功能正常的儿童中被认为相当安全。播散性卡介苗病是最严重的并发症，仅见于有潜在原发性或继发性免疫缺陷的个体。我们报告一例患有严重联合免疫缺陷（SCID）的婴儿发生播散性卡介苗病的病例，该婴儿在SCID诊断之前接种了卡介苗。
