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一名患有严重联合免疫缺陷的婴儿发生播散性卡介苗(BCG)病。

Disseminated Bacille Calmette-Guerin (BCG) disease in an infant with severe combined immunodeficiency.

作者信息

Sohail Shagufta, Afzal Muhammad, Anwar Vaqas, Shama Quratulain

机构信息

Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.

出版信息

J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S259-61.

Abstract

Bacille Calmette-Guerin (BCG) vaccine is administered to all newborns in countries where tuberculosis is still endemic. It is a live attenuated vaccine and considered quite safe in immunocompetent children. Disseminated BCG disease is the most serious complication seen only in individuals with underlying primary or secondary immunodeficiencies. We report a case of disseminated BCG disease in an infant with Severe Combined Immunodeficiency (SCID) who received BCG administration prior to diagnosis of SCID.

摘要

在结核病仍然流行的国家,所有新生儿都接种卡介苗(BCG)疫苗。它是一种减毒活疫苗,在免疫功能正常的儿童中被认为相当安全。播散性卡介苗病是最严重的并发症,仅见于有潜在原发性或继发性免疫缺陷的个体。我们报告一例患有严重联合免疫缺陷(SCID)的婴儿发生播散性卡介苗病的病例,该婴儿在SCID诊断之前接种了卡介苗。

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