Szwedziak Krzysztof, Durczyński Adam, Danilewicz Marian, Strzelczyk Janusz
Department of General and Transplant Surgery, Medical University of Lodz, Barlicki University Hospital, Lodz, Poland.
Department of Nephropathology, Medical University of Lodz, Lodz, Poland.
Contemp Oncol (Pozn). 2014;18(3):211-4. doi: 10.5114/wo.2014.41387. Epub 2014 Jun 18.
Solid pseudopapillary tumour is a rare indolent neoplasm of the pancreas (< 2% of exocrine pancreatic tumours), which predominantly affects young women at reproductive age, without significant clinical symptoms. We report a case of a 20-year-old Caucasian female who presented with upper abdominal pain of one-year duration. Ultrasound scans of the abdomen demonstrated enlarged pancreatic head and body containing a poorly separated mass (52 × 41 × 36 mm) with a multi-cystic component 20-24 mm in diameter. Laboratory tests including, tumour markers levels, were normal. She underwent complete resection of the tumour using a Beger procedure. By immunohistochemistry, the case stained strongly for CD10 and CD56 and was negative for cytokeratin-7 (CK-7), synaptophysin and chromogranin A. The proliferation index (Ki-67) was < 1%. The patient is being followed-up and remains healthy.
Solid pseudopapillary tumour is a tumour with low potential of malignancy and with generally favourable prognosis; surgical resection is usually curative.
实性假乳头状肿瘤是一种罕见的胰腺惰性肿瘤（占胰腺外分泌肿瘤的比例<2%），主要影响育龄期年轻女性，临床症状不明显。我们报告一例20岁的白种女性，有持续一年的上腹部疼痛。腹部超声扫描显示胰头和胰体增大，有一个界限不清的肿块（52×41×36mm），伴有直径20 - 24mm的多囊成分。包括肿瘤标志物水平在内的实验室检查均正常。她接受了Beger手术完整切除肿瘤。免疫组化显示，该病例CD10和CD56染色强阳性，细胞角蛋白-7（CK-7）、突触素和嗜铬粒蛋白A染色阴性。增殖指数（Ki-67）<1%。患者正在接受随访，目前健康。
实性假乳头状肿瘤是一种恶性潜能低、预后通常良好的肿瘤；手术切除通常可治愈。
