Fujishiro Jun, Sugiyama Masahiko, Ishimaru Tetsuya, Uotani Chizue, Tsuchida Shinya, Takahashi Naoto, Shiozawa Ryosuke, Takita Junko, Iwanaka Tadashi
Department of Pediatric Surgery, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.
Department of Pediatrics, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.
Pediatr Int. 2014 Dec;56(6):934-937. doi: 10.1111/ped.12399.
Herein is described a case of neonatal neuroblastoma with cyclic blood pressure fluctuation and elevated catecholamines. The fluctuations stabilized after treatment with α-adrenergic blocker and the perioperative course was uneventful. The possibility of catecholamine-related symptoms including hypertension, heart failure, and blood pressure fluctuations should be considered in the treatment for neuroblastoma; if they are present, treatment with α-blockers is effective.
本文描述了一例患有新生儿神经母细胞瘤且伴有循环血压波动和儿茶酚胺升高的病例。经α-肾上腺素能阻滞剂治疗后波动趋于稳定，围手术期过程顺利。在神经母细胞瘤的治疗中应考虑儿茶酚胺相关症状，包括高血压、心力衰竭和血压波动的可能性；如果出现这些症状，使用α-阻滞剂治疗有效。
