Kitahara K, Suzuki S, Takayama Y, Hiroe M
Kaku Igaku. 1989 Jun;26(6):773-9.
[99mTc]-pyrophosphate (PYP) and [201Tl]-chloride dual isotope single photon emission computed tomography (SPECT) is now available to detect the site and extent of acute myocardial infarction. In inflammatory myocardial disease, [99mTc]PYP makes hot image on damaged area. We performed dual isotope SPECT of [99mTc]PYP and [201Tl]Cl in two patients with acute myocarditis and severe rhythm disturbance to evaluate the severity of inflammation. Myocardial damage was estimated by [201Tl] perfusion coloring blue and myocardial inflammation was estimated by [99mTc]PYP uptake coloring red. The overlap display of both images made it clear to detect spatial extent of myocardial inflammation. Using this technique, we expect to estimate the severity of myocarditis and to make a decision of therapeutic plan.
[99mTc]焦磷酸盐（PYP）和[201Tl]氯化物双同位素单光子发射计算机断层扫描（SPECT）现已可用于检测急性心肌梗死的部位和范围。在炎症性心肌疾病中，[99mTc]PYP在受损区域形成热图像。我们对两名患有急性心肌炎和严重心律失常的患者进行了[99mTc]PYP和[201Tl]Cl双同位素SPECT检查，以评估炎症的严重程度。通过[201Tl]灌注呈蓝色来估计心肌损伤，通过[99mTc]PYP摄取呈红色来估计心肌炎症。两种图像的重叠显示清楚地检测到了心肌炎症的空间范围。使用这项技术，我们期望能够评估心肌炎的严重程度并做出治疗方案的决策。
