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荟萃分析证据如何影响口腔种植学的临床决策:德尔菲意见调查。

How meta-analytic evidence impacts clinical decision making in oral implantology: a Delphi opinion poll.

作者信息

Pommer Bernhard, Becker Kathrin, Arnhart Christoph, Fabian Ferenc, Rathe Florian, Stigler Robert G

机构信息

Academy for Oral Implantology, Vienna, Austria.

Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany.

出版信息

Clin Oral Implants Res. 2016 Mar;27(3):282-7. doi: 10.1111/clr.12528. Epub 2014 Dec 18.

Abstract

OBJECTIVES

To investigate the impact of meta-analytic evidence in scientific literature on clinical decision making in the field of oral implantology.

METHODS

A Delphi opinion poll was performed at the meeting of the "Next Generation" Committees of the Austrian, German and Swiss Societies for Implantology (ÖGI, DGI and SGI). First, the experts gave their opinion on 20 questions regarding routine implant treatment (uninformed decisions), then they were confronted with up-to-date Level I evidence from scientific literature on these topics and again asked to give their opinion (informed decisions) as well as to rate the available evidence as satisfactory or insufficient. Topics involved surgical issues, such as immediate implant placement, flapless surgery, tilted and short implants and bone substitute materials, as well as opinions on prosthodontic paradigms, such as immediate loading, abutment materials and platform switching.

RESULTS

Compared to their uninformed decisions prior to confrontation with recent scientific literature, on average, 37% of experts (range: 15-50%) changed their opinion on the topic. When originally favoring one treatment alternative, less than half were still convinced after review of meta-analytic evidence. Discrepancy between uninformed and informed decisions was significantly associated with insufficient evidence (P = 0.014, 49% change of opinion vs. 26% on topics rated as sufficiently backed with evidence). Agreement regarding strength of evidence could be reached for eight topics (40%), in three issues toward sufficiency and in five issues toward lack of evidence.

CONCLUSION

Confrontation with literature results significantly changes clinical decisions of implantologists, particularly in cases of ambiguous or lacking meta-analytic evidence.

摘要

目的

探讨科学文献中的荟萃分析证据对口腔种植学领域临床决策的影响。

方法

在奥地利、德国和瑞士种植学会(ÖGI、DGI和SGI)的“下一代”委员会会议上进行了德尔菲意见调查。首先,专家们就20个关于常规种植治疗的问题发表意见(未了解相关信息时的决策),然后他们面对这些主题的最新科学文献一级证据,并再次被要求发表意见(了解相关信息后的决策),以及将现有证据评为满意或不足。主题涉及手术问题,如即刻种植、无瓣手术、倾斜和短种植体以及骨替代材料,以及对修复范式的看法,如即刻负重、基台材料和平台转换。

结果

与在接触近期科学文献之前未了解相关信息时的决策相比,平均有37%的专家(范围:15%-50%)改变了他们对该主题的意见。当最初倾向于一种治疗方案时,在审查荟萃分析证据后,不到一半的人仍然信服。未了解相关信息时的决策与了解相关信息后的决策之间的差异与证据不足显著相关(P = 0.014,意见改变率为49%,而在被评为有充分证据支持的主题上为26%)。对于八个主题(40%)可以就证据强度达成一致,在三个问题上认为证据充分,在五个问题上认为证据不足。

结论

接触文献结果会显著改变种植医生的临床决策,特别是在荟萃分析证据不明确或缺乏的情况下。

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